Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378271 | 0.91 | ALDH1A1 (0.45) | TDP1TSPOMEN1KMT2AKEAP1 | |
| SCHEMBL10618638 | 0.90 | TDP1 (0.53) | TDP1TSPOPPARGKEAP1NFE2L2 | |
| SCHEMBL9350385 | 0.89 | NR1H4 (0.38) | TDP1NR1H4TSPOLMNAL3MBTL1 | |
| SCHEMBL9046522 | 0.82 | ALDH1A1 (0.52) | TDP1ALDH1A1MAOB | |
| SCHEMBL9839970 | 0.78 | TDP1 (0.40) | TDP1TSPOLTA4HKEAP1NFE2L2 | |
| SCHEMBL15257598 | 0.76 | TDP1 (0.60) | TDP1LMNAL3MBTL1LTA4HPPARG | |
| SCHEMBL29535405 | 0.76 | TDP1 (0.74) | TDP1LMNAL3MBTL1LTA4HPPARG | |
| SCHEMBL12280905 | 0.75 | TDP1 (0.46) | TDP1LMNAL3MBTL1MEN1HSP90AA1 | |
| SCHEMBL9353967 | 0.75 | TDP1 (0.51) | TDP1PPARGKMT2AALDH1A1 | |
| SCHEMBL10820991 | 0.74 | TDP1 (0.48) | TDP1LMNAL3MBTL1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314480-B1 | Fluorescent indicator dyes for calcium working at long wavelengths | UNIV CALIFORNIA (US) | 1994-09-14 | — | — | EP | disclosed |
| US-5049673-A | Fluorescent indicator dyes for calcium working at long wavelengths | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0314480-A2 | Fluorescent indicator dyes for calcium working at long wavelengths | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1989-05-03 | — | — | EP | disclosed |
| EP-0177202-B1 | CHELATORS WHOSE AFFINITY FOR CALCIUM IS DECREASED BY ILLUMINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1988-05-25 | — | — | EP | disclosed |
| EP-0177202-A1 | Chelators whose affinity for calcium is decreased by illumination | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1986-04-09 | — | — | EP | disclosed |