Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378271 | 0.92 | ALDH1A1 (0.45) | ALDH1A1MAOBMTNR1BTDP1MTNR1A | |
| SCHEMBL9350376 | 0.82 | TDP1 (0.46) | ALDH1A1MAOBTDP1 | |
| SCHEMBL10618638 | 0.81 | TDP1 (0.53) | MAOBTDP1 | |
| SCHEMBL14033171 | 0.78 | TDP1 (0.51) | ALDH1A1TDP1RAB9A | |
| SCHEMBL30069487 | 0.78 | TDP1 (0.69) | ALDH1A1MTNR1BTDP1MTNR1ASMN1; SMN2 | |
| SCHEMBL9164898 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAOBMTNR1BMTNR1APTPN1 | |
| SCHEMBL3994473 | 0.76 | LTA4H (0.46) | MTNR1ANOX1 | |
| SCHEMBL10360404 | 0.75 | TDP1 (0.50) | ALDH1A1TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL10378725 | 0.75 | TDP1 (0.57) | ALDH1A1MTNR1BTDP1MTNR1ANPC1 | |
| SCHEMBL21924287 | 0.75 | MAOB (0.58) | ALDH1A1MAOBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501980-A | Benzazolylcoumarin-based ion indicators | MOLECULAR PROBES, INC. (US) | 1996-03-26 | — | — | US | disclosed |