SCHEMBL9350466

SCHEMBL9350466

COc1cc(O)c(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1S(=O)(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.57
▸ KMT2A Q03164 4/20 0.57
▸ LMNA P02545 3/20 0.57
▸ ALDH1A1 P00352 2/20 0.57
▸ MPL P40238 1/20 0.43
▸ ALOX15 P16050 2/20 0.40
▸ TSHR P16473 2/20 0.40
▸ ADORA3 P0DMS8 1/20 0.40
▸ ADORA2A P29274 1/20 0.40
▸ ADORA2B P29275 1/20 0.40
▸ ADORA1 P30542 1/20 0.40
▸ CA12 O43570 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ CA9 Q16790 1/20 0.40
▸ WHR1 P49842 1/20 0.40
▸ ACLY P53396 1/20 0.40
▸ KDM4E B2RXH2 4/20 0.39
▸ HSD17B10 Q99714 3/20 0.39
▸ CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9350635 0.88 MAPT (0.47) MAPTKMT2ALMNAALDH1A1MPL
SCHEMBL9487081 0.86 MAPT (0.43) MAPTKMT2ALMNAALDH1A1ALOX15
SCHEMBL9350565 0.86 TSHR (0.51) MAPTKMT2ALMNAALDH1A1ALOX15
SCHEMBL8650450 0.86 MAPT (0.62) MAPTKMT2ALMNAALDH1A1MPL
SCHEMBL9487276 0.84 ALDH1A1 (0.41) MAPTKMT2ALMNAALDH1A1ALOX15
SCHEMBL9488116 0.82 MAPT (0.42) MAPTKMT2ALMNAALDH1A1MPL
SCHEMBL9350735 0.80 LMNA (0.46) MAPTKMT2ALMNAALDH1A1MPL
SCHEMBL15909987 0.77 ALOX15 (0.43) MAPTKMT2ALMNAALDH1A1ALOX15
SCHEMBL8083576 0.75 MAPT (0.41) MAPTKMT2ALMNAALDH1A1MPL
SCHEMBL12228370 0.73 NPC1 (0.49) MAPTKMT2ALMNAALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0205493-B1 USE OF SULFONATED 2-(2'-HYDROXYARYL)-s-TRIAZINES AS PHOTOSTABILISING AGENTS FOR WOOL AND OTHER PROTEIN FIBRES COMMW SCIENT IND RES ORG (AU) 1994-09-07 — — EP claimed
EP-0310083-B1 PROCESS FOR QUENCHING OR SUPPRESSING THE FLUORESCENCE OF OPTICALLY BRIGHTENED SUBSTRATES CIBA-GEIGY AG (CH) 1993-01-13 — — EP claimed
EP-0512946-A1 Process for improving the fastness to light of leather CIBA-GEIGY AG (CH) 1992-11-11 — — EP claimed
US-4950304-A AFTERTREATMENT OR PRETREATMENT OF NYLON TRICOT FABRICS WITH A UV ABSORBER AND FIXING CIBA-GEIGY CORPORATION (US) 1990-08-21 — — US claimed
EP-0205493-B1 USE OF SULFONATED 2-(2'-HYDROXYARYL)-s-TRIAZINES AS PHOTOSTABILISING AGENTS FOR WOOL AND OTHER PROTEIN FIBRES COMMW SCIENT IND RES ORG (AU) 1994-09-07 — — EP disclosed
EP-0245204-B1 PROCESS FOR THE PHOTOCHEMICAL STABILIZATION OF UNDYED AND DYED FIBROUS POLYAMIDE MATERIAL AND ITS MIXTURE WITH OTHER FIBRES CIBA-GEIGY AG (CH) 1993-08-04 — — EP disclosed
US-5221287-A Blend with polypropylene or polyurethane and hindered amine light stabilizer CIBA-GEIGY CORPORATION (US) 1993-06-22 — — US disclosed
EP-0512946-A1 Process for improving the fastness to light of leather CIBA-GEIGY AG (CH) 1992-11-11 — — EP disclosed
EP-0409771-A2 Process of photochemical and thermal stabilization of polyamide fibres, dyeable by acid and basic dyes, and of their mixtures amongst themselves and with other fibres CIBA-GEIGY AG (CH) 1991-01-23 — — EP disclosed
US-4950304-A AFTERTREATMENT OR PRETREATMENT OF NYLON TRICOT FABRICS WITH A UV ABSORBER AND FIXING CIBA-GEIGY CORPORATION (US) 1990-08-21 — — US disclosed
US-4874391-A USING WATER SOLUBLE COPPER COMPLEX AZO DYE, LIGHT STABILIZER AND ANTIOXIDANT CIBA-GEIGY CORPORATION (US) 1989-10-17 — — US disclosed
US-4775386-A Process for photochemical stabilization of undyed and dyed polyamide fibre material and blends thereof with other fibres: copper complex and light stabilizer treatment CIBA-GEIGY CORPORATION (US) 1988-10-04 — — US disclosed
EP-0205493-A4 USE OF SULFONATED 2-(2'-HYDROXYARYL)-s-TRIAZINES AS PHOTOSTABILISING AGENTS FOR WOOL AND OTHER PROTEIN FIBRES. COMMW SCIENT IND RES ORG (AU) 1988-09-19 — — EP disclosed
EP-0255481-A1 Process for the photochemical stabilisation of a fibrous polyamide material and its mixtures with other fibres CIBA-GEIGY AG (CH) 1988-02-03 — — EP disclosed
EP-0245204-A1 Process for the photochemical stabilization of undyed and dyed fibrous polyamide material and its mixture with other fibres CIBA-GEIGY AG (CH) 1987-11-11 — — EP disclosed
US-4698064-A Use of sulfonated 2-(2'-hydroxyaryl)-s-triazines as photostabilizing agents for wool and other protein fibres COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORG. (AU) 1987-10-06 — — US disclosed
EP-0205493-A1 USE OF SULFONATED 2-(2'-HYDROXYARYL)-s-TRIAZINES AS PHOTOSTABILISING AGENTS FOR WOOL AND OTHER PROTEIN FIBRES. COMMW SCIENT IND RES ORG (AU) 1986-12-30 — — EP disclosed
WO-1986003528-A1 USE OF SULFONATED 2-(2'-HYDROXYARYL)-s-TRIAZINES AS PHOTOSTABILISING AGENTS FOR WOOL AND OTHER PROTEIN FIBRES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 1986-06-19 — — WO disclosed
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