Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.50 |
| ▸ | NPFFR1 | Q9GZQ6 | 6/20 | 0.49 |
| ▸ | NPFFR2 | Q9Y5X5 | 6/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146667 | 0.97 | OPRM1 (0.50) | OPRM1OPRL1NPFFR1NPFFR2OPRK1 | |
| SCHEMBL9350637 | 0.87 | ALDH1A1 (0.41) | OPRM1OPRL1NPFFR1NPFFR2ALDH1A1 | |
| SCHEMBL9143220 | 0.85 | KMT2A (0.43) | OPRM1OPRL1NPFFR1NPFFR2RAB9A | |
| SCHEMBL9350621 | 0.84 | ALDH1A1 (0.41) | OPRM1OPRL1NPFFR1NPFFR2SMN1; SMN2 | |
| SCHEMBL14279001 | 0.83 | CYP3A4 (0.41) | OPRM1OPRL1NPFFR1NPFFR2NPC1 | |
| SCHEMBL9140934 | 0.82 | CYP4F2 (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9141193 | 0.82 | KMT2A (0.43) | OPRM1OPRL1NPFFR1NPFFR2RAB9A | |
| SCHEMBL9140301 | 0.80 | CYP4F2 (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2861616 | 0.79 | LMNA (0.58) | OPRM1NPFFR1NPFFR2OPRK1NPC1 | |
| SCHEMBL2877082 | 0.79 | NPFFR1 (0.56) | NPFFR1NPFFR2OPRK1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472449-B1 | Substituted sulfonamides, processes for their preparation and medicines containing them | LIPHA (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0472449-A2 | Substituted sulfonamides, processes for their preparation and medicines containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-02-26 | — | — | EP | disclosed |