Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141660 | 0.80 | CYP4F2 (0.50) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| SCHEMBL17316474 | 0.76 | CA2 (0.52) | CA2CAMK2AAKR1B1ABCC4LMNA | |
| SCHEMBL29268222 | 0.74 | CA2 (0.50) | CA2CAMK2AAKR1B1ABCC4LMNA | |
| SCHEMBL17316590 | 0.74 | CA2 (0.50) | CA2CAMK2AAKR1B1ABCC4LMNA | |
| SCHEMBL69614 | 0.73 | CA2 (0.79) | CA2CAMK2AAKR1B1ABCC4LMNA | |
| SCHEMBL9139686 | 0.72 | ALDH1A1 (0.49) | CA2CAMK2AAKR1B1ABCC4LMNA | |
| SCHEMBL9143026 | 0.72 | ALDH1A1 (0.44) | CA2CAMK2AAKR1B1ABCC4LMNA | |
| SCHEMBL1492704 | 0.72 | MAOB (1.00) | MAOAMAOBTAAR1DPP4SLC6A3 | |
| SCHEMBL933080 | 0.72 | CA2 (0.62) | CA2CAMK2AAKR1B1ABCC4LMNA | |
| SCHEMBL9250332 | 0.71 | CA2 (0.47) | CA2CAMK2AAKR1B1ABCC4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472449-B1 | Substituted sulfonamides, processes for their preparation and medicines containing them | LIPHA (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0472449-A2 | Substituted sulfonamides, processes for their preparation and medicines containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-02-26 | — | — | EP | disclosed |