SCHEMBL933080

SCHEMBL933080

NCc1ccc(CC(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.62
CAMK2A Q9UQM7 1/20 0.62
AKR1B1 P15121 1/20 0.61
LMNA P02545 2/20 0.58
GAA P10253 2/20 0.58
TSHR P16473 2/20 0.58
ABCC4 O15439 1/20 0.58
PTGS1 P23219 1/20 0.58
HTT P42858 1/20 0.58
ALDH1A1 P00352 2/20 0.52
HPGD P15428 2/20 0.52
HSD17B10 Q99714 2/20 0.52
FFAR1 O14842 1/20 0.52
ANPEP P15144 1/20 0.52
ENPEP Q07075 1/20 0.52
POLB P06746 2/20 0.50
KDM4E B2RXH2 2/20 0.50
NSD2 O96028 1/20 0.50
GRK2 P25098 1/20 0.50
CASP6 P55212 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11146854 0.98 CA2 (0.60) CA2CAMK2AAKR1B1LMNAGAA
Hydrochloric Acid SCHEMBL2575898 0.98 CA2 (0.60) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL11136721 0.93 CA2 (0.56) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL11135171 0.89 SRD5A2 (0.59) CA2CAMK2AAKR1B1LMNAGAA
Hydrochloric Acid SCHEMBL11134658 0.88 SRD5A2 (0.57) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL69614 0.87 CA2 (0.79) CA2CAMK2AAKR1B1LMNAGAA
SCHEMBL11134156 0.86 CA2 (0.48) CA2CAMK2AAKR1B1LMNAGAA
Glycine SCHEMBL2596528 0.84 GLRA1 (0.56) CA2TSHRKDM4EABATSMN1; SMN2
Hydrochloric Acid SCHEMBL25180348 0.84 CA2 (0.75) CA2CAMK2AAKR1B1LMNAGAA
Hydrochloric Acid SCHEMBL6765874 0.84 CA2 (0.75) CA2CAMK2AAKR1B1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619050-A2 DECREASED RETENTION OF MINIPROTEINS IN KIDNEY Aktis Oncology, Inc. (US) 2025-09-24 EP claimed
US-20250111889-A1 DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES UNIVERSITY OF WASHINGTON 2025-04-03 US claimed
EP-4463155-A2 DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES University of Washington (US) 2024-11-20 EP claimed
CN-118084965-B Long-acting phosphorus hapten, antigen, antibody, detection device and preparation and application thereof 广州科技贸易职业学院 2024-06-25 CN claimed
CN-118084965-A Long-acting phosphorus hapten, antigen, antibody, detection device and preparation and application thereof 广州科技贸易职业学院 2024-05-28 CN claimed
WO-2024107762-A2 DECREASED RETENTION OF MINIPROTEINS IN KIDNEY AKTIS ONCOLOGY, INC. (US) 2024-05-23 WO claimed
CN-116813497-B Amide compound and preparation method, pharmaceutical composition and application thereof 天津匠新致成科技有限公司 2023-11-14 CN claimed
WO-2023137366-A2 DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES UNIVERSITY OF WASHINGTON (US) 2023-07-20 WO claimed
US-20260116923-A1 CYCLIC PEPTIDE IL-1BETA TRAP FOR THE TREATMENT OF ATHEROSCLEROSIS AND INFLAMMATORY DISORDERS MERCK SHARP & DOHME LLC (US) 2026-04-30 US disclosed
EP-3697208-B1 HIGH-FIDELITY LONG-TERM STORAGE OF BIOLOGICAL MATERIAL CENTRE NAT RECH SCIENT (FR) 2026-04-22 EP disclosed
EP-4687443-A1 METHOD FOR FUNCTIONALISING A SOLID SUBSTRATE WITH A PEPTIDE CONJUGATE Genepep (FR) 2026-02-11 EP disclosed
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
EP-4619050-A2 DECREASED RETENTION OF MINIPROTEINS IN KIDNEY Aktis Oncology, Inc. (US) 2025-09-24 EP disclosed
EP-0386839-A2 Tetrahydroquinoline derivatives useful for neurodegenerative disorders MERCK SHARP & DOHME LTD. (GB) 1990-09-12 EP disclosed
US-4297489-A CEPHALOSPORINS BRISTOL-MYERS COMPANY (US) 1981-10-27 US disclosed
US-4179511-A Antibacterial 3-(5-tetrazolyl) penam compounds PFIZER INC. (US) 1979-12-18 US disclosed
US-4143039-A ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS PFIZER INC. (US) 1979-03-06 US disclosed
US-4115385-A PENICILLINS PFIZER INC. (US) 1978-09-19 US disclosed
US-3996201-A MOLDING CIBA-GEIGY CORPORATION (US) 1976-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 CA2 3928/4885CAMK2A 2231/4885AKR1B1 1714/4885
US-20250111889-A1 DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES DHFR, CCNH, ODC1 CA2 4658/4885CAMK2A 4398/4885AKR1B1 3107/4885
US-20260116923-A1 CYCLIC PEPTIDE IL-1BETA TRAP FOR THE TREATMENT OF ATHEROSCLEROSIS AND INFLAMMATORY DISORDERS IL1A, IL1B, IL1RN CA2 4115/4885CAMK2A 1733/4885AKR1B1 1592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.