Methacrylic Acid

Methacrylic Acid

SCHEMBL9350828

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)Sc1ccc(Sc2ccc(SC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.45
LMNA P02545 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ALDH1A1 P00352 2/20 0.44
NR1H2 P55055 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
RARB P10826 1/20 0.31
RARG P13631 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
NPC1 O15118 1/20 0.31
MITF O75030 1/20 0.31
XBP1 P17861 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
NOD2 Q9HC29 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158581 0.94 HPGD (0.50) HPGDLMNAL3MBTL1ALDH1A1NR1H2
SCHEMBL1803064 0.88 HPGD (0.39) HPGDLMNAL3MBTL1ALDH1A1NPC1
SCHEMBL27460831 0.87 HPGD (0.44) HPGDLMNAL3MBTL1ALDH1A1NR1H2
SCHEMBL7575059 0.82 L3MBTL1 (0.35) HPGDLMNAL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL544810 0.82 HPGD (0.44) HPGDLMNAALDH1A1SMN1; SMN2XBP1
SCHEMBL16170747 0.82 L3MBTL1 (0.35) HPGDLMNAL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL16170509 0.82 L3MBTL1 (0.35) HPGDLMNAL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL6568130 0.80 MAPT (0.44) HPGDLMNAALDH1A1SMN1; SMN2RAB9A
Methacrylic Acid SCHEMBL9113765 0.80 NR1H2 (0.58) HPGDLMNAL3MBTL1ALDH1A1NR1H2
SCHEMBL20094758 0.80 HPGD (0.38) HPGDLMNAL3MBTL1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0394495-B1 4,4'-BIS(METHACRYLOYLTHIO)DIPHENYL SULFIDE AND CURABLE COMPOSITION CONTAINING SAME SUMITOMO SEIKA CHEMICALS (JP) 1994-08-31 EP disclosed
US-5270439-A Method of producing a curable composition containing 4,4'-bis(methacryloylthio)diphenylsulfide SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1993-12-14 US disclosed
US-5183917-A Curable; optics, coatings, seals, adhesives, paints SHOWA DENKO K.K. (JP) 1993-02-02 US disclosed
EP-0394495-A1 4,4'-BIS(METHACRYLOYLTHIO)DIPHENYL SULFIDE AND CURABLE COMPOSITION CONTAINING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1990-10-31 EP disclosed