Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | EYA2 | O00167 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23629772 | 1.00 | HTT (0.47) | HTTAMY1ACSNK2A1POLBMAPT | |
| SCHEMBL545256 | 0.98 | HTT (0.48) | HTTAMY1ACSNK2A1POLBMAPT | |
| Hydrochloric Acid SCHEMBL934885 | 0.97 | HTT (0.47) | HTTAMY1ACSNK2A1POLBMAPT | |
| SCHEMBL935126 | 0.97 | HTT (0.47) | HTTAMY1ACSNK2A1POLBMAPT | |
| Hydrochloric Acid SCHEMBL2794700 | 0.95 | HTT (0.46) | HTTAMY1ACSNK2A1POLBMAPT | |
| SCHEMBL3962618 | 0.94 | HTT (0.47) | HTTAMY1ACSNK2A1POLBMAPT | |
| SCHEMBL16660357 | 0.91 | HTT (0.52) | HTTAMY1ACSNK2A1MAPTGAA | |
| SCHEMBL23425468 | 0.89 | POLB (0.42) | HTTAMY1ACSNK2A1POLBMAPT | |
| SCHEMBL22693634 | 0.88 | HTT (0.41) | HTTAMY1ACSNK2A1POLBMAPT | |
| SCHEMBL5268211 | 0.88 | SRC (0.43) | HTTCSNK2A1POLBMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039679-B1 | A process for the preparation of N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid and its derivatives | PRZED PROD CONSULTINGOWE ADOB SP Z O O SP K (PL) | 2015-08-12 | — | — | EP | disclosed |
| US-8629293-B2 | Process for the preparation of FE(III) chelates of N,N′-DI(2-hydroxybenzyl)-ethylenediamine-N,N′-diacetic acid and its derivatives | PRZEDSIEBIORSTWO PRODUKCYJNO-CONSULTINGOWE ADOB SP. Z O.O. SP. K. (PL) | 2014-01-14 | — | — | US | disclosed |
| US-8431734-B2 | Process for the preparation of N,N′-bis(2-hydroxybenzyl)ethylenediamine-N,N′-diacetic acid and its derivatives | Przedsiebiorstwo Produkeyjno-Consultingowe Adob SP. Z O.O. SP. K. (PL) | 2013-04-30 | — | — | US | disclosed |
| US-20120271062-A9 | PROCESS FOR THE PREPARATION OF FE(III) CHELATES OF N,N'-DI(2-HYDROXYBENZYL)-ETHYLENEDIAMINE-N,N'-DIACETIC ACID AND ITS DERIVATIVES | PRZEDSIEBIORSTWO PRODUKCYJNO-CONSULTINGOWE ADOB SP. Z O.O. (PL) | 2012-10-25 | — | — | US | disclosed |
| EP-2289869-B1 | A process for the preparation of Fe(III) chelates of N,N'-di(2-hydroxybenzyl)-ethylenediamine-N,N'-diacetic acid and its derivatives | PRZED PROD CONSULTINGOWE ADOB SP Z O O SP K (PL) | 2012-06-13 | — | — | EP | disclosed |
| US-20120108835-A1 | PROCESS FOR THE PREPARATION OF FE(III) CHELATES OF N,N'-DI(2-HYDROXYBENZYL)-ETHYLENEDIAMINE-N,N'-DIACETIC ACID AND ITS DERIVATIVES | PRZEDSIEBIORSTWO PRODUKCYJNO-CONSULTINGOWE ADOB SP. Z O.O. SP. K. (PL) | 2012-05-03 | — | — | US | disclosed |
| EP-2289869-A1 | A process for the preparation of Fe(III) chelates of N,N'-di(2-hydroxybenzyl)-ethylenediamine-N,N'-diacetic acid and its derivatives | Przedsiebiorstwo Produkcyjno-Consultingowe ADOB sp. z o.o. sp. k. (PL) | 2011-03-02 | — | — | EP | disclosed |
| WO-2011006763-A1 | A PROCESS FOR THE PREPARATION OF FE(III) CHELATES OF N,N'-DI(2-HYDROXYBENZYL)-ETHYLENEDIAMINE-N,N'-DIACETIC ACID AND ITS DERIVATIVES | PRZEDSIEBIORSTWO PRODUKCYJNO-CONSULTINGOWE ADOB SP. Z O.O. SP.K. (PL) | 2011-01-20 | — | — | WO | disclosed |
| US-20100168469-A1 | PROCESS FOR THE PREPARATION OF N,N'-BIS(2-HYDROXYBENZYL)ETHYLENEDIAMINE-N,N'-DIACETIC ACID AND ITS DERIVATIVES | PRZEDSIEBIORSTWO PRODUKCYJNO-CONSULTINGOWE ADOB SP (PL) | 2010-07-01 | — | — | US | disclosed |
| WO-2009037235-A1 | A PROCESS FOR THE PREPARATION OF N,N'-BIS(2-HYDROXYBENZYL)ETHYLENEDIAMINE-N,N'-DIACETIC ACID AND ITS DERIVATIVES | PRZEDSIEBIORSTWO PRODUKCYJNO-CONSULTINGOWE ADOB SP. Z O.O. SP. K. (PL) | 2009-03-26 | — | — | WO | disclosed |
| EP-2039679-A1 | A process for the preparation of N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid and its derivatives | Przedsiebiorstwo Produkcyjno-Consultingowe ADOB sp. z o.o. sp. k. (PL) | 2009-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108835-A1 | PROCESS FOR THE PREPARATION OF FE(III) CHELATES OF N,N'-DI(2-HYDROXYBENZYL)-ETHYLENEDIAMINE-N,N'-DIACETIC ACID AND ITS DERIVATIVES | HAO2, AOC1, HAO1 | HTT 402/4885AMY1A 3812/4885CSNK2A1 1687/4885 |
| US-20120271062-A9 | PROCESS FOR THE PREPARATION OF FE(III) CHELATES OF N,N'-DI(2-HYDROXYBENZYL)-ETHYLENEDIAMINE-N,N'-DIACETIC ACID AND ITS DERIVATIVES | HAO2, AOC1, HAO1 | HTT 402/4885AMY1A 3812/4885CSNK2A1 1687/4885 |
| US-20100168469-A1 | PROCESS FOR THE PREPARATION OF N,N'-BIS(2-HYDROXYBENZYL)ETHYLENEDIAMINE-N,N'-DIACETIC ACID AND ITS DERIVATIVES | H1-0, HAO2, HBG1 | HTT 493/4885AMY1A 2359/4885CSNK2A1 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.