Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.40 |
| ▸ | ITGAL | P20701 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936027 | 0.90 | GPR84 (0.42) | POLBGPR84ITGB2ICAM1ITGAL | |
| SCHEMBL935339 | 0.87 | GPR84 (0.41) | POLBGPR84ALDH1A1ITGB2ICAM1 | |
| SCHEMBL957431 | 0.87 | GPR84 (0.41) | POLBGPR84ALDH1A1ITGB2ICAM1 | |
| SCHEMBL955533 | 0.87 | GPR84 (0.41) | POLBGPR84ALDH1A1ITGB2ICAM1 | |
| SCHEMBL936096 | 0.83 | GPR84 (0.41) | POLBGPR84ALDH1A1ITGB2ICAM1 | |
| SCHEMBL936239 | 0.82 | SMN1; SMN2 (0.45) | POLBGPR84ALDH1A1ITGB2ICAM1 | |
| SCHEMBL935155 | 0.82 | POLB (0.42) | POLBGPR84ALDH1A1GAAMAPT | |
| SCHEMBL935459 | 0.80 | ALDH1A1 (0.42) | POLBGPR84HTTALDH1A1ITGB2 | |
| SCHEMBL935380 | 0.79 | ACE (0.41) | POLBITGB2ICAM1ITGAL | |
| SCHEMBL935379 | 0.79 | ACE (0.41) | POLBITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010748-A1 | INDOLE DERIVATIVE AND SALTINESS-STRENGTHENING AGENT CONTAINING THE DERIVATIVE | 味の素株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |