SCHEMBL935197

SCHEMBL935197

O=C(c1[c]cc[c]c1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
SRD5A2 P31213 1/20 0.42
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
AKR1C3 P42330 1/20 0.39
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
TSHR P16473 2/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
MAPT P10636 3/20 0.37
RAB9A P51151 2/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
MAPK13 O15264 1/20 0.37
MAPK12 P53778 1/20 0.37
MAPK11 Q15759 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL935016 0.85 SRD5A2 (0.54) SRD5A2HPGDPOLB
SCHEMBL11522568 0.81 HPGD (0.39) ALDH1A1TDP1KMT2AMEN1MAPT
SCHEMBL8778426 0.81 LTA4H (0.43) ALDH1A1TDP1ATMCES2CES1
SCHEMBL1260294 0.81
Water SCHEMBL29275067 0.80 ALDH1A1 (0.52) ALDH1A1TDP1L3MBTL1ATMSRD5A2
SCHEMBL619504 0.78 SNCA (0.32) ALDH1A1KMT2ACES2CES1TSHR
SCHEMBL218652 0.78 ALDH1A1 (0.54) ALDH1A1TDP1L3MBTL1ATMSRD5A2
SCHEMBL9147298 0.75 HPGD (0.38) ALDH1A1KMT2ATSHRGAAMAPK13
SCHEMBL1518068 0.74
SCHEMBL315777 0.74 ALDH1A1 (0.61) ALDH1A1TDP1L3MBTL1ATMSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10940673-B2 Methods of forming structures for downhole applications BAKER HUGHES HOLDINGS LLC (US) 2021-03-09 US claimed
US-20170297306-A1 METHODS OF FORMING STRUCTURES FOR DOWNHOLE APPLICATIONS BAKER HUGHES, A GE COMPANY, LLC 2017-10-19 US claimed
EP-2925906-B1 METHOD FOR PREPARING A HIGH TEMPERATURE POLYMER COATING BAKER HUGHES INC (US) 2017-09-27 EP claimed
CN-102471494-B star polymer Robert Bosch Ltd. (DE) 2015-11-25 CN claimed
EP-2925906-A1 METHOD FOR PREPARING A HIGH TEMPERATURE POLYMER COATING Baker Hughes Incorporated (US) 2015-10-07 EP claimed
US-8962096-B2 Method for preparing a high temperature polymer coating BAKER HUGHES INCORPORATED (US) 2015-02-24 US claimed
WO-2014084994-A1 METHOD FOR PREPARING A HIGH TEMPERATURE POLYMER COATING BAKER HUGHES INCORPORATED (US) 2014-06-05 WO claimed
US-20140147609-A1 METHOD FOR PREPARING A HIGH TEMPERATURE POLYMER COATING BAKER HUGHES HOLDINGS LLC 2014-05-29 US claimed
CN-101971394-A Composition with enhanced proton conductivity COUNCIL SCIENT IND RES 2011-02-09 CN claimed
US-7268193-B2 For producing molding compound, foam, composite, optical or opthalmic lens, dielectric film, extruded part MISSISSIPPI POLYMER TECHNOLOGIES, INC. (US) 2007-09-11 US claimed
US-6514977-B1 For treating p38 kinase mediated disorders G.D. SEARLE & COMPANY 2003-02-04 US claimed
EP-0773248-B1 Polymers with heterocyclic side groups MISSISSIPPI POLYMER TECHNOLOGI (US) 2002-10-02 EP claimed
EP-1244436-A2 COMPOUNDS AND COMPOSITIONS FOR USE IN INHIBITING ENDOPARASITIC FATTY ACID BIOSYNTHESIS UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) 2002-10-02 EP claimed
US-6423713-B1 Substituted pyrazoles as p38 kinase inhibitors G. D. SEARLE & COMPANY 2002-07-23 US claimed
WO-2001049278-A2 COMPOUNDS AND COMPOSITIONS FOR USE IN INHIBITING ENDOPARASITIC FATTY ACID BIOSYNTHESIS UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2001-07-12 WO claimed
EP-1000055-A1 SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS G.D. Searle & Co. (US) 2000-05-17 EP claimed
WO-1998052940-A1 SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS G.D. SEARLE AND CO. (US) 1998-11-26 WO claimed
US-5668245-A PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS MAXDEM INCORPORATED (US) 1997-09-16 US claimed
EP-0773248-A1 Polymers with heterocyclic side groups MAXDEM INCORPORATED (US) 1997-05-14 EP claimed
US-4158670-A QUATERNARY AMMONIUM OR PHOSPHONIUM PHASE TRANSFER AGENTS CASSELLA AKTIENGESELLSCHAFT (DE) 1979-06-19 US claimed