Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 4/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 3/20 | 0.41 |
| ▸ | FEN1 | P39748 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29249309 | 0.84 | KMT2A (0.62) | KMT2AMEN1CYP3A4HPGDKDM4E | |
| SCHEMBL31565713 | 0.80 | HDAC3 (0.39) | KMT2AMEN1CYP3A4HPGDKDM4E | |
| SCHEMBL28034427 | 0.79 | ALDH1A1 (0.63) | KMT2AMEN1CYP3A4HPGDKDM4E | |
| SCHEMBL28054494 | 0.79 | HDAC3 (0.57) | KMT2AMEN1CYP3A4HPGDKDM4E | |
| SCHEMBL9352962 | 0.79 | CA1 (0.55) | KMT2AMEN1CYP3A4HPGDKDM4E | |
| SCHEMBL9352579 | 0.78 | TSHR (0.60) | KMT2AMEN1CYP3A4HPGDKDM4E | |
| SCHEMBL315781 | 0.78 | ALDH1A1 (0.60) | KMT2AMEN1KDM4EMAPTALOX15 | |
| SCHEMBL6631999 | 0.77 | GSK3B (0.59) | CES1FOLH1IDO1PTPN1 | |
| SCHEMBL306422 | 0.77 | MAPT (0.53) | KMT2AMEN1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL10645186 | 0.76 | ALDH1A1 (0.58) | KMT2AMEN1KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412933-B1 | Coating compositions | CIBA GEIGY AG (CH) | 1994-09-14 | — | — | EP | disclosed |
| US-5183842-A | Mixture of ketoacid and amine with film-forming binder, curing | CIBA-GEIGY CORPORATION (US) | 1993-02-02 | — | — | US | disclosed |
| US-5128396-A | Corrosion inhibiting primers on metallic substrates | CIBA-GEIGY CORPORATION (US) | 1992-07-07 | — | — | US | disclosed |