Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.65 |
| ▸ | CA2 | P00918 | 9/20 | 0.65 |
| ▸ | CA7 | P43166 | 4/20 | 0.65 |
| ▸ | CA9 | Q16790 | 4/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.65 |
| ▸ | CA12 | O43570 | 3/20 | 0.65 |
| ▸ | CA3 | P07451 | 3/20 | 0.65 |
| ▸ | CA4 | P22748 | 3/20 | 0.65 |
| ▸ | CA6 | P23280 | 3/20 | 0.65 |
| ▸ | CA5A | P35218 | 3/20 | 0.65 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18426393 | 0.79 | CA1 (1.00) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9352633 | 0.78 | CA1 (0.58) | CA1CA2CA7CA9CA14 | |
| SCHEMBL9352647 | 0.76 | CA1 (0.61) | CA1CA2CA7CA9CA14 | |
| Indapamide SCHEMBL29496872 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9CA14 | |
| Indapamide SCHEMBL29377544 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9CA14 | |
| Indapamide SCHEMBL29372690 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9CA14 | |
| Indapamide SCHEMBL41303 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9CA14 | |
| Indapamide SCHEMBL163266 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9CA14 | |
| Indapamide SCHEMBL476213 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9CA14 | |
| Indapamide SCHEMBL2329030 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324184-B1 | 2-Amino-1,2,3,4-tetrahydroisoquinoline derivatives, method for their preparation and their use as medicines | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1994-09-28 | — | — | EP | disclosed |