Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317738 | 0.84 | MAOB (0.49) | ALOX5PRMT5WDR77 | |
| SCHEMBL5266330 | 0.84 | MAOB (0.49) | ALOX5PRMT5WDR77 | |
| SCHEMBL11146097 | 0.77 | TDP1 (0.54) | ALOX5TDP1RAB9A | |
| SCHEMBL22816808 | 0.77 | GSTP1 (0.50) | — | |
| SCHEMBL421030 | 0.74 | ALOX15 (0.50) | PRMT5WDR77RAB9A | |
| SCHEMBL2572521 | 0.74 | PRMT5 (0.46) | PRMT5WDR77TDP1 | |
| SCHEMBL10041855 | 0.74 | MAOB (0.50) | RAB9A | |
| SCHEMBL1257312 | 0.73 | RAB9A (0.50) | PRMT5WDR77RAB9A | |
| SCHEMBL17072360 | 0.72 | GSTP1 (0.49) | RAB9A | |
| SCHEMBL8994871 | 0.72 | RAB9A (0.67) | ALOX5TLR4TLR2RAB9AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375452-B1 | Cycloalkane derivatives | ICI PLC (GB) | 1994-10-05 | — | — | EP | disclosed |
| US-5105020-A | Lopoxygerase inhibitors; antiinflammatory agents, antiallergens | IMPERIAL CHEMISTRIES INDUSTRIES PLC (GB) | 1992-04-14 | — | — | US | disclosed |
| EP-0375452-A2 | Cycloalkane derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-27 | — | — | EP | disclosed |