Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CDC42 | P60953 | 1/20 | 0.48 |
| ▸ | RAC1 | P63000 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059358 | 0.87 | PTGS2 (0.57) | KDM4EMTNR1AMTNR1BAKR1C3AKR1C2 | |
| SCHEMBL6280665 | 0.87 | MTNR1A (0.48) | KDM4EMTNR1AMTNR1BAKR1C3AKR1C2 | |
| SCHEMBL7031139 | 0.87 | PTGS2 (0.57) | KDM4EMTNR1AMTNR1BAKR1C3AKR1C2 | |
| Ammonia Solution, Strong SCHEMBL10891516 | 0.85 | PTGS2 (0.56) | KDM4EMTNR1AMTNR1BAKR1C3AKR1C2 | |
| SCHEMBL27890994 | 0.85 | PTGS2 (0.56) | KDM4EMTNR1AMTNR1BAKR1C3AKR1C2 | |
| SCHEMBL9483087 | 0.83 | MTNR1A (0.47) | KDM4EMTNR1AMTNR1BCYP1A2TSHR | |
| SCHEMBL7379672 | 0.83 | AKR1C3 (0.60) | KDM4EMTNR1AMTNR1BAKR1C3AKR1C2 | |
| SCHEMBL3929101 | 0.80 | CYP2D6 (0.50) | KDM4EMTNR1AMTNR1BCYP1A2CYP2A6 | |
| SCHEMBL3929104 | 0.80 | CYP2D6 (0.50) | KDM4EMTNR1AMTNR1BCYP1A2CYP2A6 | |
| SCHEMBL27581533 | 0.79 | MTNR1A (0.46) | KDM4EMTNR1AMTNR1BAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461958-B1 | 2-(aminoalkyl)-5-(arylalkyl)1,3-dioxanderivatives their production and their use in therapeutics | SYNTHELABO (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0461958-A1 | 2-(aminoalkyl)-5-(arylalkyl)1,3-dioxanderivatives their production and their use in therapeutics | SYNTHELABO (FR) | 1991-12-18 | — | — | EP | disclosed |