Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237340 | 0.90 | LMNA (0.40) | LMNACYP2C19HIF1A | |
| SCHEMBL6879887 | 0.87 | LMNA (0.40) | LMNA | |
| SCHEMBL5482338 | 0.87 | LMNA (0.40) | LMNA | |
| SCHEMBL5356462 | 0.87 | LMNA (0.40) | LMNA | |
| SCHEMBL9356454 | 0.86 | LMNA (0.48) | LMNACYP2C19HIF1A | |
| SCHEMBL9191546 | 0.84 | LMNA (0.40) | LMNA | |
| SCHEMBL8978138 | 0.84 | LMNA (0.62) | LMNA | |
| SCHEMBL9260881 | 0.84 | LMNA (0.62) | LMNA | |
| SCHEMBL11512552 | 0.82 | LMNA (0.40) | LMNA | |
| SCHEMBL11512416 | 0.81 | LMNA (0.40) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557345-B1 | 1,3-BIS- 3-(MONO- OR POLY-HYDROXY)ACYLAMINO-5-(MONO- OR POLY-HYDROXYALKYL)AMINOCARBONYL-2,4,6-TRIIODO-BENZOYL-AMINO]-HYDROXY- OR HYDROXYALKYL-PROPANES, THEIR METHODS OF PREPARATION AND X-RAY CONTRAST MEDIA CONTAINING THEM | DIBRA SPA (IT) | 1994-09-14 | — | — | EP | disclosed |
| WO-1992008691-A1 | 1,3-BIS-[3-(MONO- OR POLY-HYDROXY)ACYLAMINO-5-(MONO- OR POLY-HYDROXYALKYL)AMINOCARBONYL-2,4,6-TRIIODO-BENZOYL-AMINO]-HYDROXY- OR HYDROXYALKYL-PROPANES, THEIR METHODS OF PREPARATION AND X-RAY CONTRAST MEDIA CONTAINING THEM | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1992-05-29 | — | — | WO | disclosed |