SCHEMBL8978138

SCHEMBL8978138

CC(=O)O[C@@H](C)C(=O)Nc1c(I)c(C(=O)Cl)c(I)c(C(=O)NC(CO)CO)c1I

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9260881 1.00 LMNA (0.62) LMNA
SCHEMBL7050768 0.94 LMNA (0.70) LMNA
SCHEMBL14334595 0.94 LMNA (0.70) LMNA
SCHEMBL7764898 0.90 LMNA (0.64) LMNA
SCHEMBL20468079 0.87 LMNA (0.60) LMNA
SCHEMBL9352691 0.87 LMNA (0.49) LMNA
SCHEMBL6879887 0.87 LMNA (0.40) LMNA
SCHEMBL5356462 0.87 LMNA (0.40) LMNA
SCHEMBL5482338 0.87 LMNA (0.40) LMNA
SCHEMBL9191546 0.84 LMNA (0.40) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707572-A1 IODINATED OLIGOMERIC COMPOUNDS AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME BRACCO S.p.A. (IT) 1996-04-24 EP disclosed
WO-1995001966-A1 IODINATED OLIGOMERIC COMPOUNDS AND DIAGNOSTIC COMPOSITIONS CONTAINING THE SAME BRACCO S.P.A. (IT) 1995-01-19 WO disclosed