Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353097 | 0.90 | NPC1 (0.44) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8463757 | 0.87 | NPC1 (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7223364 | 0.82 | POLB (0.45) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL7230766 | 0.81 | POLB (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1201738 | 0.80 | AKR1B1 (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7225323 | 0.78 | HDAC3 (0.42) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL8467038 | 0.78 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7223994 | 0.78 | POLB (0.36) | KMT2AMEN1ALDH1A1RAB9AKDM4E | |
| SCHEMBL7228473 | 0.78 | MAPT (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7222688 | 0.77 | HDAC3 (0.44) | KMT2AMEN1ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469888-B1 | Amidobenzenes | ICI PLC (GB) | 1994-09-28 | — | — | EP | claimed |
| EP-0469888-A1 | Amidobenzenes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-05 | — | — | EP | claimed |