Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353090 | 0.90 | KMT2A (0.52) | NPC1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL8463757 | 0.84 | NPC1 (0.55) | NPC1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7223364 | 0.79 | POLB (0.45) | NPC1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL7230766 | 0.78 | POLB (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7225323 | 0.76 | HDAC3 (0.42) | MEN1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL8467038 | 0.76 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8958259 | 0.76 | RAB9A (0.34) | S1PR4MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL7228473 | 0.75 | MAPT (0.40) | NPC1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7223994 | 0.75 | POLB (0.36) | MEN1KMT2AALDH1A1RAB9ALMNA | |
| SCHEMBL7222688 | 0.75 | HDAC3 (0.44) | MEN1KMT2AALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469888-B1 | Amidobenzenes | ICI PLC (GB) | 1994-09-28 | — | — | EP | claimed |
| EP-0469888-A1 | Amidobenzenes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-05 | — | — | EP | claimed |