Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | C1R | P00736 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576213 | 0.88 | ALDH1A1 (0.44) | MAPK1KMT2ATDP1ALDH1A1C1R | |
| SCHEMBL8574670 | 0.88 | C1R (0.47) | MAPK1KMT2ATDP1ALDH1A1C1R | |
| SCHEMBL8574639 | 0.87 | KEAP1 (0.46) | MAPK1KMT2ATDP1ALDH1A1C1R | |
| SCHEMBL9349485 | 0.87 | KEAP1 (0.46) | KMT2AALDH1A1LTB4RKEAP1NFE2L2 | |
| SCHEMBL8574327 | 0.85 | KEAP1 (0.47) | MAPK1KMT2AALDH1A1C1RKEAP1 | |
| SCHEMBL18114374 | 0.82 | KEAP1 (0.48) | MAPK1KMT2AALDH1A1C1RKEAP1 | |
| SCHEMBL9353204 | 0.78 | KEAP1 (0.50) | MAPK1KMT2AALDH1A1C1RKEAP1 | |
| SCHEMBL8577911 | 0.76 | C1R (0.49) | MAPK1KMT2ATDP1ALDH1A1C1R | |
| SCHEMBL8577942 | 0.76 | KMT2A (0.43) | MAPK1KMT2ATDP1ALDH1A1KEAP1 | |
| SCHEMBL8578075 | 0.76 | LMNA (0.36) | MAPK1KMT2ATDP1ALDH1A1C1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273115-B1 | Chemiluminescent acridinium and phenanthridinium salts | ABBOTT LAB (US) | 1994-09-07 | — | — | EP | disclosed |