Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.35 |
| ▸ | RXRB | P28702 | 5/20 | 0.35 |
| ▸ | RXRG | P48443 | 5/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12943838 | 0.94 | RXRA (0.38) | RXRARXRBRXRGRARA | |
| SCHEMBL26081392 | 0.76 | RXRA (0.37) | RXRARXRBRXRGRARA | |
| SCHEMBL954866 | 0.76 | AR (0.41) | — | |
| SCHEMBL1003882 | 0.75 | HSP90AA1 (0.47) | — | |
| SCHEMBL22320162 | 0.75 | RXRA (0.36) | RXRARXRBRXRGRARA | |
| SCHEMBL24359494 | 0.73 | EGFR (0.39) | RXRARXRBRXRGRARA | |
| SCHEMBL20620701 | 0.72 | SLC22A12 (0.36) | — | |
| Lithium SCHEMBL29601477 | 0.72 | EGFR (0.38) | RXRARXRBRXRGRARA | |
| SCHEMBL12943752 | 0.71 | HSP90AA1 (0.43) | RXRARXRBRXRGRARA | |
| SCHEMBL4857923 | 0.68 | RXRA (0.61) | RXRARXRBRXRGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456793-A1 | CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS | Equistar Chemicals, LP (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-2456795-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | Equistar Chemicals, LP (US) | 2012-05-30 | — | — | EP | disclosed |
| US-8158733-B2 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158733-B2 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158733-B2 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP (US) | 2012-04-17 | — | — | US | disclosed |
| US-8153544-B2 | Method for preparing non-metallocene catalysts | EQUISTAR CHEMICALS, LP (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153544-B2 | Method for preparing non-metallocene catalysts | EQUISTAR CHEMICALS, LP (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153544-B2 | Method for preparing non-metallocene catalysts | EQUISTAR CHEMICALS, LP (US) | 2012-04-10 | — | — | US | disclosed |
| WO-2011011039-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20110021344-A1 | Method for preparing non-metallocene ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| US-20110021344-A1 | Method for preparing non-metallocene ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| WO-2011011039-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20110021344-A1 | Method for preparing non-metallocene ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| US-20110021727-A1 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| US-20110021727-A1 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| US-20110021727-A1 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| WO-2011011040-A1 | CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | disclosed |