Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12950642 | 0.84 | AR (0.46) | ARBACE1HSP90AA1 | |
| SCHEMBL956042 | 0.83 | HSP90AA1 (0.45) | ARBACE1HSP90AA1 | |
| SCHEMBL3278157 | 0.81 | NQO2 (0.37) | ARMEN1KMT2ANPC1RAB9A | |
| SCHEMBL935336 | 0.76 | RXRA (0.35) | — | |
| SCHEMBL13580645 | 0.73 | NQO2 (0.32) | NQO2TDO2 | |
| SCHEMBL13398891 | 0.72 | TDO2 (0.45) | NPC1RAB9ATDO2HSP90AA1 | |
| SCHEMBL31759105 | 0.72 | CTSS (0.39) | MEN1KMT2AATMTDO2HSP90AA1 | |
| SCHEMBL12943838 | 0.71 | RXRA (0.38) | — | |
| SCHEMBL14817161 | 0.71 | RARG (0.40) | HSP90AA1 | |
| SCHEMBL1003882 | 0.70 | HSP90AA1 (0.47) | ARHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456793-A1 | CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS | Equistar Chemicals, LP (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-2456795-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | Equistar Chemicals, LP (US) | 2012-05-30 | — | — | EP | disclosed |
| US-8158733-B2 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158733-B2 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158733-B2 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP (US) | 2012-04-17 | — | — | US | disclosed |
| US-8153544-B2 | Method for preparing non-metallocene catalysts | EQUISTAR CHEMICALS, LP (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153544-B2 | Method for preparing non-metallocene catalysts | EQUISTAR CHEMICALS, LP (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153544-B2 | Method for preparing non-metallocene catalysts | EQUISTAR CHEMICALS, LP (US) | 2012-04-10 | — | — | US | disclosed |
| WO-2011011039-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | disclosed |
| WO-2011011039-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20110021344-A1 | Method for preparing non-metallocene ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| US-20110021344-A1 | Method for preparing non-metallocene ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| US-20110021344-A1 | Method for preparing non-metallocene ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| US-20110021727-A1 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| US-20110021727-A1 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| US-20110021727-A1 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| WO-2011011040-A1 | CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | disclosed |
| WO-2011011040-A1 | CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | disclosed |