Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353154 | 0.82 | GAA (0.31) | — | |
| SCHEMBL7565114 | 0.81 | EPHX1 (0.56) | ACHEEPHX1 | |
| SCHEMBL9189503 | 0.81 | EPHX1 (0.56) | ACHEEPHX1 | |
| SCHEMBL677759 | 0.81 | EPHX1 (0.56) | ACHEEPHX1 | |
| SCHEMBL677758 | 0.79 | ACHE (0.59) | ACHENAAAEPHX1 | |
| SCHEMBL6688663 | 0.79 | ACHE (0.53) | ACHEEPHX1 | |
| SCHEMBL9481159 | 0.79 | GAA (0.58) | FAAH | |
| SCHEMBL6688659 | 0.77 | ACHE (0.56) | ACHEEPHX1 | |
| Iodocarb SCHEMBL114369 | 0.77 | ACHE (0.59) | ACHEEPHX1 | |
| SCHEMBL11308601 | 0.77 | NAAA (0.47) | ACHENAAAEPHX1FAAHRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490566-B1 | Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents | ROHM & HAAS (US) | 1994-10-12 | — | — | EP | claimed |
| US-5209930-A | PREPARATION AND USE OF N-IODOPROPARGYL OXYCARBONYL AMINO ACID ESTERS AND DERIVATIVES AS ANTIMICROBIAL AGENTS | ROHM AND HAAS COMPANY (US) | 1993-05-11 | — | — | US | claimed |
| EP-0490566-A1 | Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | claimed |
| EP-0490566-B1 | Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents | ROHM & HAAS (US) | 1994-10-12 | — | — | EP | disclosed |
| US-5209930-A | PREPARATION AND USE OF N-IODOPROPARGYL OXYCARBONYL AMINO ACID ESTERS AND DERIVATIVES AS ANTIMICROBIAL AGENTS | ROHM AND HAAS COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0490566-A1 | Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |