Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049493 | 0.89 | TET2 (0.41) | GAAALDH1A1HSD17B10 | |
| SCHEMBL9353138 | 0.85 | EGLN1 (0.36) | ALDH1A1 | |
| SCHEMBL9480027 | 0.84 | TDP1 (0.39) | GAAALDH1A1 | |
| SCHEMBL9481781 | 0.83 | GAA (0.33) | GAA | |
| SCHEMBL9353452 | 0.82 | ACHE (0.46) | — | |
| SCHEMBL9480089 | 0.81 | LMNA (0.50) | ALDH1A1 | |
| SCHEMBL9480116 | 0.80 | GAA (0.42) | GAAALDH1A1 | |
| SCHEMBL9479997 | 0.79 | — | — | |
| SCHEMBL7573517 | 0.78 | CHRNB2 (0.40) | ALDH1A1 | |
| SCHEMBL677163 | 0.76 | ACHE (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490566-B1 | Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents | ROHM & HAAS (US) | 1994-10-12 | — | — | EP | claimed |
| US-5209930-A | PREPARATION AND USE OF N-IODOPROPARGYL OXYCARBONYL AMINO ACID ESTERS AND DERIVATIVES AS ANTIMICROBIAL AGENTS | ROHM AND HAAS COMPANY (US) | 1993-05-11 | — | — | US | claimed |
| EP-0490566-A1 | Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | claimed |
| EP-0490566-B1 | Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents | ROHM & HAAS (US) | 1994-10-12 | — | — | EP | disclosed |
| US-5209930-A | PREPARATION AND USE OF N-IODOPROPARGYL OXYCARBONYL AMINO ACID ESTERS AND DERIVATIVES AS ANTIMICROBIAL AGENTS | ROHM AND HAAS COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0490566-A1 | Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |