Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 4/20 | 0.39 |
| ▸ | TK1 | P04183 | 5/20 | 0.39 |
| ▸ | TK2 | O00142 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9354258 | 0.88 | TYMP (0.40) | MAPK1HPGDTYMPTK1TK2 | |
| SCHEMBL8761117 | 0.86 | UPP1 (0.36) | TK1 | |
| SCHEMBL8761065 | 0.76 | — | — | |
| SCHEMBL9353843 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL9353735 | 0.75 | MAPK1 (0.41) | MAPK1HPGDTYMPTK1TK2 | |
| SCHEMBL9353968 | 0.74 | MAPK1 (0.36) | MAPK1HPGDTYMPTK1TK2 | |
| SCHEMBL9354282 | 0.73 | DUT (0.39) | — | |
| SCHEMBL9354248 | 0.73 | HPGD (0.41) | MAPK1HPGDTYMPTK1TK2 | |
| SCHEMBL10602520 | 0.72 | TYMP (0.49) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL7219926 | 0.72 | MAPK1 (0.54) | MAPK1HPGDTYMPTK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371139-B1 | 6-SUBSTITUTED ACYCLICPYRIMIDINE NUCLEOSIDE DERIVATIVES AND ANTIVIRAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENTS | MITSUBISHI CHEM IND (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5112835-A | 6-SUBSTITUTED ACYCLOPYRIMIDINE NUCLEOSIDE DERIVATIVES AND ANTIVIRAL AGENTS CONTAINING THE SAME AS ACTIVE INGREDIENT THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0371139-A1 | 6-SUBSTITUTED ACYCLICPYRIMIDINE NUCLEOSIDE DERIVATIVES AND ANTIVIRAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENTS | Mitsubishi Chemical Corporation (JP) | 1990-06-06 | — | — | EP | disclosed |