Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517682 | 0.79 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL5520896 | 0.79 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL5517717 | 0.79 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL2955749 | 0.74 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL3909140 | 0.74 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL619757 | 0.74 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL23066399 | 0.72 | LMNA (1.00) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Sorbitol SCHEMBL763 | 0.72 | LMNA (1.00) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL2297640 | 0.72 | LMNA (1.00) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL20594082 | 0.72 | LMNA (1.00) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425565-B1 | SILICON COMPOUNDS IN BONE TREATMENT | ETHYL CORP (US) | 1994-09-21 | — | — | EP | disclosed |
| US-5183061-A | Administering a compound in which silicon is solely bonded to oxygen or halogen, not less than one-fourth of valences bonding to oxygen | ETHYL CORPORATION (US) | 1993-02-02 | — | — | US | disclosed |
| EP-0425565-A4 | SILICON COMPOUNDS IN BONE TREATMENT | — | 1992-01-02 | — | — | EP | disclosed |
| EP-0425565-A1 | SILICON COMPOUNDS IN BONE TREATMENT. | ETHYL CORP (US) | 1991-05-08 | — | — | EP | disclosed |
| US-4917045-A | ADMINISTERING TO FERTILE EGG TO STIMULATE BONE GROWTH | ETHYL CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |
| WO-1990000884-A1 | SILICON COMPOUNDS IN BONE TREATMENT | ETHYL CORPORATION (US) | 1990-02-08 | — | — | WO | disclosed |