SCHEMBL5517682

SCHEMBL5517682

C[Si](C)(C)OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
KDM4E B2RXH2 2/20 0.41
PDE4A P27815 1/20 0.37
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
TOP1 P11387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5517717 1.00 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL5520896 1.00 LMNA (0.50) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL9355138 0.79 LMNA (0.52) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL92729 0.73 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL2297555 0.73 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL1668363 0.73 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL19741239 0.73 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL1964137 0.73 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL6700235 0.73 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL4996629 0.73 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070042030-A1 Preparation for the application of agents in mini-droplets IDEA AG (DE) 2007-02-22 US disclosed
EP-0475160-B2 Preparation for drug application in minute droplet form IDEA AG (DE) 2004-07-14 EP disclosed
US-6165500-A Preparation for the application of agents in mini-droplets IDEA AG (DE) 2000-12-26 US disclosed
EP-0475160-B1 Preparation for drug application in minute droplet form IDEA AG (DE) 1996-02-14 EP disclosed
EP-0475160-A1 Preparation for drug application in minute droplet form Cevc, Gregor, Prof. Dr. (DE) 1992-03-18 EP disclosed
WO-1992003122-A1 PREPARATION FOR APPLICATION OF ACTIVE SUBSTANCES IN THE FORM OF MINIMUM-SIZED DROPLETS CEVC GREGOR (DE) 1992-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042030-A1 Preparation for the application of agents in mini-droplets FABP4, NPC1L1, LIPA LMNA 327/4885L3MBTL1 3706/4885TDP1 4661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.