SCHEMBL9355431

SCHEMBL9355431

O=P(O)(O)c1ccccc1OCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2B Q14289 2/20 1.00
ALPG P10696 1/20 1.00
POLB P06746 3/20 0.64
NPC1 O15118 3/20 0.64
ALDH1A1 P00352 2/20 0.62
RAB9A P51151 1/20 0.62
ESR1 P03372 1/20 0.58
YWHAB P31946 1/20 0.58
PDK1 Q15118 1/20 0.58
TSHR P16473 1/20 0.52
PTPRC P08575 1/20 0.51
PTPN2 P17706 1/20 0.51
PTPN1 P18031 1/20 0.51
PTPRB P23467 1/20 0.51
PTPN6 P29350 1/20 0.51
PTPN11 Q06124 1/20 0.51
SGMS2 Q8NHU3 2/20 0.50
LIPE Q05469 1/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15264456 0.88 PTK2B (0.77) PTK2BALPGPOLBNPC1ALDH1A1
SCHEMBL5861973 0.82 ALPG (0.70) PTK2BALPGNPC1ALDH1A1TSHR
SCHEMBL2614391 0.81 PTK2B (0.72) PTK2BALPGPOLBNPC1ALDH1A1
SCHEMBL10039996 0.79 PTK2B (0.89) PTK2BALPGPOLBNPC1ALDH1A1
SCHEMBL9751692 0.78 POLB (0.68) PTK2BALPGPOLBNPC1ALDH1A1
SCHEMBL2614392 0.78 POLB (1.00) PTK2BALPGPOLBNPC1ALDH1A1
SCHEMBL3247277 0.78 PTK2B (0.68) PTK2BALPGPOLBNPC1ALDH1A1
SCHEMBL10039991 0.78 PTK2B (0.63) PTK2BALPGPOLBNPC1ALDH1A1
SCHEMBL31306499 0.77 PTK2B (0.60) PTK2BALPGPOLBNPC1RAB9A
SCHEMBL7021385 0.77 ALPG (0.61) PTK2BALPGNPC1RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0439470-B1 PROCESS FOR INCREASING THE MOLECULAR WEIGHT OF A POLYAMIDE DU PONT (US) 1994-11-02 EP claimed
EP-0439470-A1 PROCESS FOR INCREASING THE MOLECULAR WEIGHT OF A POLYAMIDE. DU PONT (US) 1991-08-07 EP claimed
US-4966949-A PHENYLPHOSPHINIC ACID DERIVATIVES; HIGH STRENGTH MATERIAL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-30 US claimed
WO-1990004614-A1 PROCESS FOR INCREASING THE MOLECULAR WEIGHT OF A POLYAMIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-03 WO claimed
CN-103415586-B Polyester resin composition for electrical/electronic component sealing material, package, and method for producing same TOYOBO CO.,LTD. (JP) 2016-04-06 CN disclosed
EP-0439470-B1 PROCESS FOR INCREASING THE MOLECULAR WEIGHT OF A POLYAMIDE DU PONT (US) 1994-11-02 EP disclosed
EP-0439470-A1 PROCESS FOR INCREASING THE MOLECULAR WEIGHT OF A POLYAMIDE. DU PONT (US) 1991-08-07 EP disclosed
US-4966949-A PHENYLPHOSPHINIC ACID DERIVATIVES; HIGH STRENGTH MATERIAL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-30 US disclosed
WO-1990004614-A1 PROCESS FOR INCREASING THE MOLECULAR WEIGHT OF A POLYAMIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-03 WO disclosed