Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231433 | 0.89 | ALDH1A1 (0.43) | HSD11B1HSD17B3ALDH1A1TSHRTDP1 | |
| SCHEMBL11421838 | 0.83 | GABRA1 (0.38) | ALDH1A1TSHRTDP1CYP3A4CYP1A2 | |
| Catechol SCHEMBL9355747 | 0.82 | ALDH1A1 (0.44) | HSD11B1HSD17B3ALDH1A1TSHRTDP1 | |
| SCHEMBL11431393 | 0.81 | GABRA1 (0.37) | ALDH1A1TSHRTDP1CYP3A4CYP1A2 | |
| SCHEMBL8519938 | 0.75 | POLB (0.36) | ALDH1A1TSHRTDP1CYP3A4CYP1A2 | |
| SCHEMBL29413912 | 0.75 | POLB (0.36) | ALDH1A1TSHRTDP1CYP3A4CYP1A2 | |
| SCHEMBL27889522 | 0.75 | APEX1 (0.41) | HSD11B1HSD17B3ALDH1A1TSHRTDP1 | |
| SCHEMBL4154409 | 0.73 | TSHR (0.39) | ALDH1A1TSHRTDP1CYP3A4CYP1A2 | |
| SCHEMBL11254545 | 0.72 | ALDH1A1 (0.45) | ALDH1A1TSHRTDP1CYP1A2CYP2C19 | |
| SCHEMBL5865457 | 0.72 | GABRA1 (0.38) | ALDH1A1TSHRTDP1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254348-B1 | PROCESS OF (CO)POLYMERIZATION OF ALPHA-OLEFINS IN THE PRESENCE OF ANTIOXIDANTS | ENICHEM SYNTHESIS S.p.A. (IT) | 1993-08-25 | — | — | EP | claimed |
| US-4824885-A | PHOSPHITES OR PHOSPHONITES | ENICHEM SINTESI S.P.A. (IT) | 1989-04-25 | — | — | US | claimed |
| EP-0254348-A2 | Process of (co)polymerization of alpha-olefins in the presence of antioxidants | ENICHEM SYNTHESIS S.p.A. (IT) | 1988-01-27 | — | — | EP | claimed |
| EP-0416321-B1 | Crystalline polyolefin composition | CHISSO CORP (JP) | 1994-11-09 | — | — | EP | disclosed |
| EP-0254348-B1 | PROCESS OF (CO)POLYMERIZATION OF ALPHA-OLEFINS IN THE PRESENCE OF ANTIOXIDANTS | ENICHEM SYNTHESIS S.p.A. (IT) | 1993-08-25 | — | — | EP | disclosed |
| US-5063264-A | Molding materials | CHISSO CORPORATION (JP) | 1991-11-05 | — | — | US | disclosed |
| EP-0416321-A1 | Crystalline polyolefin composition | Chisso Corporation (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4824885-A | PHOSPHITES OR PHOSPHONITES | ENICHEM SINTESI S.P.A. (IT) | 1989-04-25 | — | — | US | disclosed |
| EP-0254348-A2 | Process of (co)polymerization of alpha-olefins in the presence of antioxidants | ENICHEM SYNTHESIS S.p.A. (IT) | 1988-01-27 | — | — | EP | disclosed |