Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CD69 | Q07108 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525106 | 0.92 | CYP1A2 (0.37) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3417517 | 0.85 | CYP2C19 (0.42) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10814715 | 0.82 | EZH2 (0.33) | ALDH1A1ALOX15MAPTL3MBTL1 | |
| SCHEMBL11488213 | 0.81 | CYP1A2 (0.36) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11294608 | 0.78 | CYP1A2 (0.33) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| Catechol SCHEMBL9355747 | 0.77 | ALDH1A1 (0.44) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27757864 | 0.77 | CA2 (0.34) | TSHRALDH1A1TDP1RXRA | |
| SCHEMBL11421838 | 0.77 | GABRA1 (0.38) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5865457 | 0.77 | GABRA1 (0.38) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27737123 | 0.76 | CA2 (0.36) | TSHRCYP2C9ALDH1A1TDP1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054698-A1 | Granular Polymer Additives and Their Preparation | ALBEMARLE CORPORATION (US) | 2009-02-26 | — | — | US | disclosed |
| US-7425290-B2 | Compaction; dry granulation; uniform mixture; steric hindrance phenolic compound and polymer; forming paste; compression, shaping; drying | ALBEMARLE CORPORATION (US) | 2008-09-16 | — | — | US | disclosed |
| US-20050009725-A1 | Compaction; dry granulation; uniform mixture; steric hindrance phenolic compound and polymer; forming paste; compression, shaping; drying | ALBEMARLE CORPORATION | 2005-01-13 | — | — | US | disclosed |
| US-6821456-B2 | STERICALLY-HINDERED PHENOLIC COMPOUND MIXTURE; INTERBONDS IN SITU WITH DESOLVATED SURFACES | ALBEMARLE CORPORATION | 2004-11-23 | — | — | US | disclosed |
| EP-1383833-A1 | GRANULAR POLYMER ADDITIVES AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1363972-A1 | GRANULAR POLYMER ADDITIVES AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2003-11-26 | — | — | EP | disclosed |
| US-20030193041-A1 | Sterically-hindered phenolic compound mixture; interbonds in situ with desolvated surfaces | ALBEMARLE CORPORATION | 2003-10-16 | — | — | US | disclosed |
| US-6515052-B2 | Granular polymer additives and their preparation | ALBEMARLE CORPORATION | 2003-02-04 | — | — | US | disclosed |
| WO-2002068523-A1 | GRANULAR POLYMER ADDITIVES AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002068524-A1 | GRANULAR POLYMER ADDITIVES AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2002-09-06 | — | — | WO | disclosed |
| US-20020117651-A1 | Granular polymer additives and their preparation | ALBEMARLE CORPORATION | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054698-A1 | Granular Polymer Additives and Their Preparation | GRN, C9, COG4 | TSHR 4509/4885CYP1A2 2404/4885CYP3A4 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.