Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246632 | 0.81 | LCK (0.47) | ALDH1A1TSHRKCNN4LCKPPARD | |
| SCHEMBL3502125 | 0.77 | — | — | |
| SCHEMBL28292106 | 0.74 | DGAT1 (0.39) | ALDH1A1TSHRKCNN4DGAT1SRC | |
| SCHEMBL6897321 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| SCHEMBL11022237 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| SCHEMBL1691839 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| SCHEMBL25325252 | 0.71 | HMGCR (0.42) | ALDH1A1TSHRKCNN4DGAT1SRC | |
| SCHEMBL1854077 | 0.70 | — | — | |
| SCHEMBL6755569 | 0.70 | DGAT1 (0.39) | ALDH1A1TSHRKCNN4DGAT1SRC | |
| SCHEMBL8370081 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRLCKPPARDZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299513-B1 | Azetidine derivatives, compositions and their use | FIDIA GEORGETOWN INST (US) | 1994-10-05 | — | — | EP | disclosed |
| US-4990504-A | Modulate excitatory amino acid receptor system | FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) | 1991-02-05 | — | — | US | disclosed |
| US-4946839-A | ALZHEIMER'S DISEASE | FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) | 1990-08-07 | — | — | US | disclosed |
| EP-0299513-A1 | Azetidine derivatives, compositions and their use | FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) | 1989-01-18 | — | — | EP | disclosed |