SCHEMBL1246632

SCHEMBL1246632

COC(=O)C(C)(Br)CCCC(Br)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.47
PPARD Q03181 1/20 0.47
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
ZDHHC7 Q9NXF8 1/20 0.40
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
KCNN4 O15554 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
DGAT1 O75907 1/20 0.31
ACACB O00763 1/20 0.30
ACACA Q13085 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5087836 0.81 ZDHHC7 (0.34) ZDHHC7CA1CA2DGAT1
SCHEMBL9356331 0.81 ALDH1A1 (0.37) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL6755569 0.80 DGAT1 (0.39) ALDH1A1TSHRKMT2AKCNN4CA1
SCHEMBL3208305 0.73 NAALAD2 (0.42) ALDH1A1TSHRMEN1KMT2AKCNN4
SCHEMBL29184392 0.72 ELANE (0.37) ZDHHC7ALDH1A1TSHRMEN1KMT2A
SCHEMBL7887196 0.72 TSHR (0.54) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL7887199 0.72 TSHR (0.54) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL19357554 0.71 LCK (0.55) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL1449604 0.71 LCK (0.73) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL2122342 0.71 LCK (0.65) LCKPPARDZDHHC20ZDHHC2ZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2550307-B1 MACRO-PHOTOINITIATORS AND CURABLE COMPOSITIONS THEREOF Henkel IP & Holding GmbH (DE) 2017-11-22 EP disclosed
US-9096936-B2 Metal structural body-containing polymer film, method for manufacturing metal structural body-containing polymer film, and method for manufacturing patterned structural body CANON KABUSHIKI KAISHA (JP) 2015-08-04 US disclosed
US-20140217063-A1 METAL STRUCTURAL BODY-CONTAINING POLYMER FILM, METHOD FOR MANUFACTURING METAL STRUCTURAL BODY-CONTAINING POLYMER FILM, AND METHOD FOR MANUFACTURING PATTERNED STRUCTURAL BODY CANON KABUSHIKI KAISHA (JP) 2014-08-07 US disclosed
US-8748503-B2 Macro-photoinitiators and curable compositions thereof Henkel US IP LLC (US) 2014-06-10 US disclosed
EP-2550307-A2 MACRO-PHOTOINITIATORS AND CURABLE COMPOSITIONS THEREOF Henkel Corporation (US) 2013-01-30 EP disclosed
US-20130018122-A1 MACRO-PHOTOINITIATORS AND CURABLE COMPOSITIONS THEREOF HENKEL CORPORATION (US) 2013-01-17 US disclosed
WO-2011119272-A2 MACRO-PHOTOINITIATORS AND CURABLE COMPOSITIONS THEREOF HENKEL CORPORATION (US) 2011-09-29 WO disclosed
EP-2192932-B1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON INC (CH) 2011-05-04 EP disclosed
US-7888403-B2 soft foldable intraocular lenses with no glistenings or vacuoles when stored in water; monofunctional phenyl or alkylphenyl acrylate or acrylamide and difunctional acrylate or acrylamide monomers; a di- or tri-block acrylic macromer ALCON, INC. (CH) 2011-02-15 US disclosed
US-20100204418-A1 Method for Producing Silane-Modified Copolymers CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2010-08-12 US disclosed
US-20100147796-A1 METAL STRUCTURAL BODY-CONTAINING POLYMER FILM, METHOD FOR MANUFACTURING METAL STRUCTURAL BODY-CONTAINING POLYMER FILM, AND METHOD FOR MANUFACTURING PATTERNED STRUCTURAL BODY CANON KABUSHIKI KAISHA (JP) 2010-06-17 US disclosed
EP-2192932-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS Alcon, Inc. (CH) 2010-06-09 EP disclosed
WO-2009046232-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2009-04-09 WO disclosed
US-20090093592-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2009-04-09 US disclosed
US-20080305143-A1 Controlled Radical Polymerization-Derived Block Copolymer Compositions for Medical Device Coatings MEDTRONIC VASCULAR, INC. (US) 2008-12-11 US disclosed
EP-1940484-A1 CONTROLLED RADICAL POLYMERIZATION-DERIVED BLOCK COPOLYMER COMPOSITIONS FOR MEDICAL DEVICE COATINGS Medtronic Vascular, Inc. (US) 2008-07-09 EP disclosed
WO-2007024500-A1 CONTROLLED RADICAL POLYMERIZATION-DERIVED BLOCK COPOLYMER COMPOSITIONS FOR MEDICAL DEVICE COATINGS MEDTRONIC VASCULAR, INC. (US) 2007-03-01 WO disclosed