Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.57 |
| ▸ | CHAT | P28329 | 4/20 | 0.56 |
| ▸ | APEX1 | P27695 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.55 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.55 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11320857 | 0.90 | CHAT (0.51) | HPGDSCHATAPEX1USP2ENPP3 | |
| SCHEMBL11342346 | 0.87 | CTDSP1 (0.47) | HPGDSCHATAPEX1USP2ENPP3 | |
| SCHEMBL15894776 | 0.86 | CHAT (0.52) | HPGDSCHATAPEX1USP2ENPP3 | |
| SCHEMBL9360776 | 0.84 | CHAT (0.59) | HPGDSCHATAPEX1USP2ENPP3 | |
| SCHEMBL2201232 | 0.84 | ENPP2 (0.44) | HPGDSCHATAPEX1USP2ENPP3 | |
| SCHEMBL12935282 | 0.84 | ENPP2 (0.44) | HPGDSCHATAPEX1USP2ENPP3 | |
| SCHEMBL12646669 | 0.83 | HPGDS (0.46) | HPGDSCHATAPEX1USP2ENPP3 | |
| SCHEMBL4425719 | 0.83 | CHAT (0.43) | HPGDSCHATAPEX1USP2ENPP3 | |
| Calcium SCHEMBL2221866 | 0.83 | CHAT (0.43) | HPGDSCHATAPEX1USP2ENPP3 | |
| SCHEMBL2222351 | 0.83 | CHAT (0.46) | HPGDSCHATAPEX1USP2ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356014-B1 | Reactive Dyes | ZENECA LTD (GB) | 1994-11-30 | — | — | EP | disclosed |
| EP-0356014-A1 | Reactive Dyes | ZENECA LIMITED (GB) | 1990-02-28 | — | — | EP | disclosed |