Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 4/20 | 0.59 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.59 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | APEX1 | P27695 | 2/20 | 0.58 |
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.49 |
| ▸ | FUT8 | Q9BYC5 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
| ▸ | P2RY13 | Q9BPV8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310040 | 0.84 | CHAT (0.51) | CHATENPP3ENPP1USP2APEX1 | |
| SCHEMBL4106042 | 0.84 | CA9 (0.53) | CHATENPP3ENPP1FUT8CA12 | |
| SCHEMBL9357003 | 0.84 | HPGDS (0.57) | CHATENPP3ENPP1USP2APEX1 | |
| SCHEMBL30268659 | 0.83 | CHAT (0.52) | CHATENPP3ENPP1USP2APEX1 | |
| SCHEMBL114494 | 0.83 | CHAT (0.52) | CHATENPP3ENPP1USP2APEX1 | |
| SCHEMBL9326023 | 0.81 | CHAT (0.59) | CHATENPP3ENPP1USP2APEX1 | |
| SCHEMBL11353679 | 0.81 | P2RY12 (0.54) | CHATENPP3ENPP1USP2APEX1 | |
| SCHEMBL6849679 | 0.80 | CHAT (0.63) | CHATENPP3ENPP1USP2APEX1 | |
| SCHEMBL11879794 | 0.79 | CA12 (0.49) | CHATENPP3ENPP1USP2APEX1 | |
| SCHEMBL11881901 | 0.79 | ENPP2 (0.49) | CHATENPP3ENPP1USP2APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356014-B1 | Reactive Dyes | ZENECA LTD (GB) | 1994-11-30 | — | — | EP | disclosed |
| EP-0356014-A1 | Reactive Dyes | ZENECA LIMITED (GB) | 1990-02-28 | — | — | EP | disclosed |