Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391505 | 1.00 | LMNA (0.52) | LMNAHTTGPR3MEN1KMT2A | |
| SCHEMBL196601 | 0.77 | GPR3 (0.64) | LMNAHTTGPR3MEN1KMT2A | |
| SCHEMBL29461212 | 0.76 | TDP1 (0.54) | LMNAHTTGPR3MEN1KMT2A | |
| SCHEMBL856788 | 0.76 | TDP1 (0.54) | LMNAHTTGPR3MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL2184448 | 0.76 | GPR3 (0.61) | LMNAHTTGPR3MEN1KMT2A | |
| SCHEMBL31391484 | 0.75 | CYP1A2 (0.41) | LMNACYP1A2ALDH1A1KDM4ENQO2 | |
| SCHEMBL18544725 | 0.74 | LMNA (0.52) | LMNAHTTGPR3MEN1KMT2A | |
| SCHEMBL3340310 | 0.74 | DCPS (0.63) | LMNAHTTGPR3KMT2ACYP1A2 | |
| SCHEMBL29663295 | 0.74 | DCPS (0.63) | LMNAHTTGPR3KMT2ACYP1A2 | |
| SCHEMBL28855851 | 0.74 | LMNA (0.52) | LMNAHTTGPR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731216-A1 | HETEROARYL-AMINE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | Augustine Therapeutics (BE) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024261329-A1 | HETEROARYL-AMINE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2024-12-26 | — | — | WO | disclosed |
| WO-2023118507-A2 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2023-06-29 | — | — | WO | disclosed |
| EP-0285089-B1 | 4-Thioquinazoline derivatives, processes for their preparation and pharmaceutical compositions | NISSHIN FLOUR MILLING CO (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-4829069-A | 4-Thioquinazoline derivatives as antiulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| US-4060615-A | ANTIHYPERTENSIVE, PHOSPHODIESTERASE INHIBITOR | MEAD JOHNSON & COMPANY (US) | 1977-11-29 | — | — | US | disclosed |