SCHEMBL9358196

SCHEMBL9358196

O=C(O)CCC(NC(=O)c1cccc(Cl)c1)C(=O)NC1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
CCKBR P32239 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9358206 1.00 NPC1 (0.61) NPC1RAB9ACCKBR
SCHEMBL9358275 0.91 NPC1 (0.64) NPC1RAB9ACCKBR
SCHEMBL2245220 0.82 ADAMTS5 (0.57) NPC1RAB9A
SCHEMBL2245703 0.82 ADAMTS5 (0.57) NPC1RAB9A
SCHEMBL2244951 0.81 ADAMTS5 (0.58) NPC1RAB9A
SCHEMBL15323778 0.77 NPC1 (1.00) NPC1RAB9A
SCHEMBL2246450 0.76 ADAMTS5 (0.61) NPC1RAB9A
SCHEMBL9358631 0.76 CCKBR (0.77) CCKBR
SCHEMBL15326419 0.76 L3MBTL1 (1.00) NPC1RAB9A
SCHEMBL9358372 0.75 CCKBR (0.76) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0498830-B1 GLUTAMIC AND ASPARTIC ACID DERIVATIVES WITH ANTIGASTRIN ACTIVITY AND A METHOD FOR THEIR PREPARATION ROTTA RESEARCH LAB (IT) 1994-12-14 EP claimed