Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023377 | 0.95 | HTR5A (0.46) | HTR5ADRD2DRD3ALDH1A1ADRA2B | |
| SCHEMBL18053266 | 0.89 | HTR5A (0.46) | HTR5ADRD2DRD3ALDH1A1ADRA2B | |
| SCHEMBL20445640 | 0.79 | KDM1A (0.47) | KDM1AALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL26889686 | 0.79 | HTR5A (0.42) | HTR5ADRD2DRD3ALDH1A1ADRA2B | |
| SCHEMBL9457900 | 0.77 | HTR5A (0.40) | HTR5ADRD2DRD3MEN1KMT2A | |
| SCHEMBL3908655 | 0.76 | HTR5A (0.39) | HTR5ADRD2DRD3MEN1KMT2A | |
| SCHEMBL29823229 | 0.76 | DRD2 (0.49) | HTR5ADRD2DRD3ALDH1A1ADRA2B | |
| SCHEMBL13999138 | 0.76 | DRD2 (0.49) | HTR5ADRD2DRD3ALDH1A1ADRA2B | |
| SCHEMBL17014343 | 0.75 | HTR5A (0.47) | HTR5ADRD2DRD3ALDH1A1ADRA2B | |
| SCHEMBL9358616 | 0.74 | BCL2L1 (0.47) | DRD2DRD3KDM1AALDH1A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032218-A1 | HETEROCYCLIC THR-β RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREFOR | 苏州闻天医药科技有限公司 | 2021-02-25 | — | — | WO | disclosed |
| EP-0418064-B1 | Naphthalene and tetrahydronaphthalene gem-diphosphonate derivatives | SYMPHAR SA (CH) | 1994-12-14 | — | — | EP | disclosed |
| US-5204336-A | Anticholestrol agents | SYMPHAR S.A. (CH) | 1993-04-20 | — | — | US | disclosed |
| EP-0418064-A2 | Naphthalene and tetrahydronaphthalene gem-diphosphonate derivatives | SYMPHAR S.A. (CH) | 1991-03-20 | — | — | EP | disclosed |