Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 2/20 | 0.49 |
| ▸ | CCR5 | P51681 | 2/20 | 0.49 |
| ▸ | CCR8 | P51685 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466188 | 0.88 | PARP1 (0.56) | PARP1KDM4EPSMD14COPS5CCR1 | |
| SCHEMBL7460486 | 0.86 | LMNA (0.64) | PARP1KDM4EPSMD14COPS5CCR1 | |
| SCHEMBL434888 | 0.79 | HPGDS (0.62) | PARP1KDM4EPSMD14COPS5CCR1 | |
| SCHEMBL27190487 | 0.77 | KDM4E (0.59) | KDM4EPSMD14HPGDSLMNAMETAP2 | |
| SCHEMBL9355371 | 0.76 | PARP1 (0.74) | PARP1KDM4EPSMD14COPS5CCR1 | |
| SCHEMBL1398196 | 0.76 | CYP1A2 (0.41) | PARP1KDM4ECYP1A2NPSR1ALDH1A1 | |
| SCHEMBL3415803 | 0.76 | LMNA (0.71) | KDM4ELMNAMETAP2METAP1HDAC6 | |
| SCHEMBL10768382 | 0.75 | LMNA (0.47) | KDM4EHPGDSLMNAMETAP2METAP1 | |
| SCHEMBL20181093 | 0.75 | MAPT (0.54) | PARP1KDM4EPSMD14COPS5CCR1 | |
| SCHEMBL7623213 | 0.75 | MAPT (0.38) | KDM4ELMNAMETAP2METAP1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417543-B1 | Process for the preparation of 3-methylquinolin-8-carboxylic acid | BASF AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| EP-0417543-B1 | Process for the preparation of 3-methylquinolin-8-carboxylic acid | BASF AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| EP-0417543-A2 | Process for the preparation of 3-methylquinolin-8-carboxylic acid | BASF Aktiengesellschaft (DE) | 1991-03-20 | — | — | EP | disclosed |
| EP-0417543-A2 | Process for the preparation of 3-methylquinolin-8-carboxylic acid | BASF Aktiengesellschaft (DE) | 1991-03-20 | — | — | EP | disclosed |