Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RHOC | P08134 | 1/20 | 0.32 |
| ▸ | RHOA | P61586 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402654 | 0.87 | PTPRC (0.34) | TDP1KDM4EELANEKMT2AALDH1A1 | |
| SCHEMBL9402901 | 0.86 | ELANE (0.36) | TDP1KDM4EELANERECQLSMN1; SMN2 | |
| SCHEMBL9402717 | 0.86 | HDAC3 (0.36) | TDP1ELANENR1H4 | |
| SCHEMBL9359357 | 0.85 | MAP2K1 (0.38) | TDP1ELANEKMT2A | |
| SCHEMBL9402931 | 0.85 | RAB9A (0.48) | ELANELMNANR1H4NPC1RAB9A | |
| SCHEMBL9402914 | 0.84 | RAB9A (0.50) | KDM4ESRD5A2NPC1RAB9A | |
| SCHEMBL9402628 | 0.83 | ELANE (0.36) | TDP1KDM4EELANEKMT2AALDH1A1 | |
| SCHEMBL9402588 | 0.83 | ALDH1A1 (0.45) | TDP1KDM4EELANESMN1; SMN2KMT2A | |
| SCHEMBL9359013 | 0.83 | ELANE (0.39) | TDP1KDM4EELANERECQLKMT2A | |
| SCHEMBL9402942 | 0.82 | ELANE (0.41) | TDP1KDM4EELANERECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463989-B1 | N-oxyimidic acid derivatives | SANDOZ LTD (CH) | 1994-12-28 | — | — | EP | claimed |
| EP-0463989-A1 | N-oxyimidic acid derivatives | SANDOZ LTD. (CH) | 1992-01-02 | — | — | EP | claimed |
| EP-0463989-B1 | N-oxyimidic acid derivatives | SANDOZ LTD (CH) | 1994-12-28 | — | — | EP | disclosed |
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |
| EP-0463989-A1 | N-oxyimidic acid derivatives | SANDOZ LTD. (CH) | 1992-01-02 | — | — | EP | disclosed |