Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402776 | 0.93 | KDM4E (0.47) | ELANECYP1A2TDP1KDM4EMAPT | |
| SCHEMBL9402882 | 0.91 | MAPT (0.43) | ELANECYP1A2CYP2C9TDP1NPC1 | |
| SCHEMBL9402614 | 0.90 | CYP1A2 (0.41) | CYP1A2CYP2C9KDM4EMAPTHSD17B10 | |
| SCHEMBL9402620 | 0.89 | MAPT (0.46) | ELANECYP1A2CYP2C9KDM4EMAPT | |
| SCHEMBL9402700 | 0.89 | MAPT (0.50) | ELANECYP1A2CYP2C9NPC1MAPT | |
| SCHEMBL9402942 | 0.87 | ELANE (0.41) | ELANECYP2C9TDP1NPC1KDM4E | |
| SCHEMBL9402745 | 0.87 | TDP1 (0.44) | ELANETDP1MAPTLMNAALDH1A1 | |
| SCHEMBL9402779 | 0.87 | CYP1A2 (0.39) | CYP1A2CYP2C9NPC1KDM4EMAPT | |
| SCHEMBL9402901 | 0.87 | ELANE (0.36) | ELANETDP1NPC1KDM4EMAPT | |
| SCHEMBL9402795 | 0.85 | TDP1 (0.39) | ELANECYP2C9TDP1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463989-B1 | N-oxyimidic acid derivatives | SANDOZ LTD (CH) | 1994-12-28 | — | — | EP | claimed |
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | claimed |
| EP-0463989-A1 | N-oxyimidic acid derivatives | SANDOZ LTD. (CH) | 1992-01-02 | — | — | EP | claimed |
| EP-0463989-B1 | N-oxyimidic acid derivatives | SANDOZ LTD (CH) | 1994-12-28 | — | — | EP | disclosed |
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |
| EP-0463989-A1 | N-oxyimidic acid derivatives | SANDOZ LTD. (CH) | 1992-01-02 | — | — | EP | disclosed |