Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9359110 | 0.95 | KMT2A (0.48) | KMT2ANPSR1ELANESMN1; SMN2RAB9A | |
| SCHEMBL9359262 | 0.87 | HTR1B (0.38) | KMT2AELANEALDH1A1MAPTCYP1A2 | |
| SCHEMBL9359225 | 0.87 | HTR1B (0.38) | KMT2AELANEALDH1A1MAPTCYP1A2 | |
| SCHEMBL9359229 | 0.87 | HTR1B (0.38) | KMT2AELANEALDH1A1MAPTCYP1A2 | |
| SCHEMBL9363320 | 0.84 | NPC1 (0.45) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL9358949 | 0.84 | ESR1 (0.41) | KMT2AELANERAB9ANPC1LMNA | |
| SCHEMBL9359049 | 0.83 | SLC6A4 (0.40) | KMT2ANPSR1ELANESMN1; SMN2RAB9A | |
| SCHEMBL9595848 | 0.81 | DRD4 (0.39) | KMT2AELANEALDH1A1LMNAMAPT | |
| SCHEMBL9359328 | 0.81 | PTGS2 (0.47) | — | |
| SCHEMBL9359221 | 0.80 | ALDH1A1 (0.46) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363782-B1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | ERBA CARLO SPA (IT) | 1994-01-05 | — | — | EP | claimed |
| US-5272144-A | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines and pharmaceutical use | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-12-21 | — | — | US | claimed |
| WO-1990003965-A1 | ARYLOXY-, ARYLTHIO-, HETEROARYLOXY-, HETEROARYLTHIO-ALKENYLENE DERIVATIVES OF AMINES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-04-19 | — | — | WO | claimed |
| EP-0363782-A1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-04-18 | — | — | EP | claimed |
| EP-0363782-B1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | ERBA CARLO SPA (IT) | 1994-01-05 | — | — | EP | disclosed |
| US-5272144-A | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines and pharmaceutical use | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-12-21 | — | — | US | disclosed |
| EP-0363782-A1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-04-18 | — | — | EP | disclosed |