Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596666 | 0.83 | LMNA (0.44) | L3MBTL1ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL7298723 | 0.77 | AKR1C3 (0.50) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL7298719 | 0.77 | AKR1C3 (0.50) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL15941381 | 0.77 | MEN1 (0.66) | NPC1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL1006524 | 0.77 | AKR1C3 (0.48) | L3MBTL1ALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL9363622 | 0.76 | MEN1 (0.44) | NPC1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL28807454 | 0.75 | KMT2A (0.50) | L3MBTL1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9562317 | 0.74 | MEN1 (0.45) | ALDH1A1MEN1KMT2AAKR1C3ABCG2 | |
| SCHEMBL29145676 | 0.74 | MEN1 (0.61) | NPC1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL10436436 | 0.74 | MCL1 (0.47) | NPC1L3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363782-B1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | ERBA CARLO SPA (IT) | 1994-01-05 | — | — | EP | disclosed |
| US-5272144-A | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines and pharmaceutical use | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-12-21 | — | — | US | disclosed |
| WO-1990003965-A1 | ARYLOXY-, ARYLTHIO-, HETEROARYLOXY-, HETEROARYLTHIO-ALKENYLENE DERIVATIVES OF AMINES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-04-19 | — | — | WO | disclosed |
| EP-0363782-A1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-04-18 | — | — | EP | disclosed |