Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397476 | 0.85 | ABCG2 (0.53) | MEN1KMT2AABCG2AKR1C3RECQL | |
| SCHEMBL28732347 | 0.85 | ABCG2 (0.53) | MEN1KMT2AABCG2AKR1C3RECQL | |
| SCHEMBL29082928 | 0.84 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7298719 | 0.82 | AKR1C3 (0.50) | MEN1KMT2AABCG2AKR1C3RAD51 | |
| SCHEMBL7298723 | 0.82 | AKR1C3 (0.50) | MEN1KMT2AABCG2AKR1C3RAD51 | |
| SCHEMBL15941381 | 0.82 | MEN1 (0.66) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1006524 | 0.82 | AKR1C3 (0.48) | MEN1KMT2AAKR1C3RAD51ALDH1A1 | |
| SCHEMBL9359402 | 0.81 | ATM (0.50) | MEN1KMT2AABCG2AKR1C3RAD51 | |
| SCHEMBL21187006 | 0.81 | KDM4E (0.52) | MEN1KMT2ARAD51ALDH1A1 | |
| SCHEMBL14458708 | 0.81 | KDM4E (0.52) | MEN1KMT2ARAD51ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010161-A1 | POLYMER REVERSAL ON SOLID SURFACES | AFFYMAX TECHNOLOGIES N.V. (AN) | 1993-05-27 | — | — | WO | disclosed |