Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29082922 | 0.88 | CYP1B1 (0.42) | AKR1C3AKR1C1CYP3A4CYP2C9KMT2A | |
| SCHEMBL9130439 | 0.86 | TRPM8 (0.49) | AKR1C3CYP3A4KMT2AMEN1ALDH1A1 | |
| SCHEMBL9130445 | 0.86 | TRPM8 (0.49) | AKR1C3CYP3A4KMT2AMEN1ALDH1A1 | |
| SCHEMBL7298723 | 0.85 | AKR1C3 (0.50) | AKR1C3KMT2ARAD51MEN1ALDH1A1 | |
| SCHEMBL7298719 | 0.85 | AKR1C3 (0.50) | AKR1C3KMT2ARAD51MEN1ALDH1A1 | |
| SCHEMBL10436436 | 0.85 | MCL1 (0.47) | AKR1C3AKR1C1KMT2ARAD51MEN1 | |
| SCHEMBL1004802 | 0.83 | ATM (0.44) | AKR1C3RAD51ALDH1A1ATMTDP1 | |
| SCHEMBL1004800 | 0.83 | ATM (0.44) | AKR1C3RAD51ALDH1A1ATMTDP1 | |
| SCHEMBL7831754 | 0.83 | KMT2A (0.54) | KMT2AMEN1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7831757 | 0.83 | KMT2A (0.54) | KMT2AMEN1ALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053321-B1 | SUBSTITUTED DERIVATIVES OF PHENOXY CINNAMIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1985-05-29 | — | — | EP | claimed |
| US-4435496-A | WITH FREE RADICAL PHOTOSENSITIZER | AMERICAN HOECHST CORPORATION (US) | 1984-03-06 | — | — | US | claimed |
| US-4435208-A | Herbicidally active substituted phenoxycinnamic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-06 | — | — | US | claimed |
| US-4230492-A | P-CHLOROBENZENESULFONIC ACID, DIAZO RESIN | THE RICHARDSON COMPANY (US) | 1980-10-28 | — | — | US | claimed |
| US-4225661-A | DIAZO RESIN LAYER, PHOTOCHROMIC DYE AND ADDITION POLYMER OVERLAYER | THE RICHARDSON COMPANY (US) | 1980-09-30 | — | — | US | claimed |
| CN-109312203-A | Assign the quantum spot film adhesive composition and its quantum spot film, back light unit and display device including it of low-moisture permeability | 株式会社薇姿凯慕 | 2019-02-05 | — | — | CN | disclosed |
| US-20110092732-A1 | APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-04-21 | — | — | US | disclosed |
| EP-2275398-A1 | APPLICATION OF THE IRIDIUM COMPLEX IN ASYMMETRIC CATALYTIC HYDROGENATION FOR UNSATURATED CARBOXYLIC ACID | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-01-19 | — | — | EP | disclosed |
| EP-0575802-B1 | Photopolymeric printing plates | KODAK POLYCHROME GRAPHICS CO (US) | 1999-02-24 | — | — | EP | disclosed |
| US-5550215-A | FORMING POLYMER ON SUBSTRATE WITH A TETHER MOLECULE; CYCLIZATION; DEPROTECTING; DECYCLIZATION | AFFYMETRIX, INC. | 1996-08-27 | — | — | US | disclosed |
| US-5340681-A | Forming photopolymerizable mixture of encapsulated pigment, monomers or polymers, photoinitiators, and diazonium compound on substrate | INTERNATIONAL PAPER COMPANY (US) | 1994-08-23 | — | — | US | disclosed |
| US-5286594-A | Nontacky, mar resistant, easily developed durable plates | INTERNATIONAL PAPER COMPANY (US) | 1994-02-15 | — | — | US | disclosed |
| US-4330611-A | Lithographic plate and photoresist having photosensitive layers of diazo and cinnamoylated polyvinyl alcohol materials | RICHARDSON GRAPHICS COMPANY (US) | 1982-05-18 | — | — | US | disclosed |
| US-4273851-A | Method of coating using photopolymerizable latex systems | RICHARDSON GRAPHICS COMPANY (US) | 1981-06-16 | — | — | US | disclosed |
| US-4263392-A | EXTRACTING DIAZONIUM COMPOUND | RICHARDSON GRAPHICS COMPANY (US) | 1981-04-21 | — | — | US | disclosed |
| US-4230492-A | P-CHLOROBENZENESULFONIC ACID, DIAZO RESIN | THE RICHARDSON COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| US-4225661-A | DIAZO RESIN LAYER, PHOTOCHROMIC DYE AND ADDITION POLYMER OVERLAYER | THE RICHARDSON COMPANY (US) | 1980-09-30 | — | — | US | disclosed |
| US-4224398-A | Photopolymerizable latex systems | RICHARDSON GRAPHICS COMPANY (US) | 1980-09-23 | — | — | US | disclosed |
| US-4186069-A | PARTICLES OF WATER-INSOLUBLE POLYMERS IN COMBINATION WITH WATER-SOLUBLE, LIGHT-SENSITIVE POLYMERS | RICHARDSON GRAPHICS COMPANY (US) | 1980-01-29 | — | — | US | disclosed |
| US-4133685-A | Lithographic plate and photoresist having photosensitive layers of diazo and cinnamoylated polyvinyl alcohol materials | RICHARDSON CHEMICAL COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092732-A1 | APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS | HDHD5, ELOVL5, FASN | AKR1C3 740/4885AKR1C1 645/4885CYP3A4 1172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.