Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 8/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363341 | 0.82 | OPRM1 (0.37) | LMNAGAAALDH1A1MAPT | |
| SCHEMBL9864996 | 0.77 | BCHE (0.52) | BCHEACHEMAOB | |
| SCHEMBL9363032 | 0.76 | BCHE (0.52) | BCHEACHEMAOBAPP | |
| SCHEMBL9937345 | 0.75 | OPRM1 (0.39) | LMNAGAANPSR1ALDH1A1MAPT | |
| SCHEMBL9970976 | 0.71 | MAPK14 (0.37) | LMNANPSR1ALDH1A1MAPT | |
| SCHEMBL19624830 | 0.70 | BCHE (0.67) | BCHEACHEMAOBAPPALDH1A1 | |
| SCHEMBL14376127 | 0.69 | BCHE (0.70) | BCHEACHEMAOBAPPALDH1A1 | |
| SCHEMBL27188920 | 0.69 | BRD4 (0.43) | L3MBTL1LMNAGAANPSR1ALDH1A1 | |
| SCHEMBL14376652 | 0.69 | BCHE (0.70) | BCHEACHEMAOBAPPALDH1A1 | |
| SCHEMBL4733853 | 0.67 | SMN1; SMN2 (0.45) | ACHEL3MBTL1MAOBNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383318-B1 | Aralkylamine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5180746-A | Cholinesterase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0383318-A2 | Aralkylamine compounds | Takeda Chemical Industries, Ltd. (JP) | 1990-08-22 | — | — | EP | disclosed |