Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9970976 | 0.91 | MAPK14 (0.37) | OPRM1MAPK14ALDH1A1BRD4MEN1 | |
| SCHEMBL9363341 | 0.83 | OPRM1 (0.37) | OPRM1MAPK14ALDH1A1BRD4MEN1 | |
| SCHEMBL7737588 | 0.83 | ALDH1A1 (0.44) | OPRM1ALDH1A1BRD4MEN1MAPT | |
| SCHEMBL16153701 | 0.81 | ALDH1A1 (0.41) | OPRM1ALDH1A1BRD4MEN1MAPT | |
| SCHEMBL8871499 | 0.80 | OPRM1 (0.40) | OPRM1MAPK14ALDH1A1BRD4MEN1 | |
| SCHEMBL15016426 | 0.76 | NPC1 (0.40) | MAPK14ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL1270456 | 0.76 | TGM2 (0.39) | MAPTKDM4E | |
| SCHEMBL28615338 | 0.75 | SMN1; SMN2 (0.39) | MAPK14ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL9359209 | 0.75 | BCHE (0.42) | ALDH1A1MAPTLMNANPSR1GAA | |
| SCHEMBL11477738 | 0.74 | SMN1; SMN2 (0.55) | ALDH1A1BRD4MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946280-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| US-8946280-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| US-8946280-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-03 | — | — | US | disclosed |
| EP-2651890-B1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| EP-2651890-B1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| US-20130303375-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-14 | — | — | US | disclosed |
| US-20130303375-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-14 | — | — | US | disclosed |
| US-20130303375-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-14 | — | — | US | disclosed |
| EP-2651890-A1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | Syngenta Participations AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080115-A1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303375-A1 | PLANT GROWTH REGULATING COMPOUNDS | AREG, GHITM, FGF1 | OPRM1 3255/4885MAPK14 435/4885ALDH1A1 3820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.