Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402878 | 0.87 | KMT2A (0.49) | KMT2ARAB9ANPC1HDAC3HDAC4 | |
| SCHEMBL9704727 | 0.86 | KMT2A (0.56) | KMT2ARAB9ANPC1HDAC3HDAC4 | |
| SCHEMBL9359357 | 0.82 | MAP2K1 (0.38) | KMT2AACSS2 | |
| SCHEMBL9402922 | 0.81 | RAB9A (0.69) | KMT2ARAB9ANPC1HDAC3HDAC4 | |
| SCHEMBL9402803 | 0.79 | RAB9A (0.40) | KMT2ARAB9ANPC1MLYCD | |
| SCHEMBL21894152 | 0.79 | CA1 (0.64) | KMT2ARAB9ANPC1MAPTCA1 | |
| SCHEMBL9402928 | 0.79 | HDAC3 (0.45) | KMT2ARAB9ANPC1HDAC3HDAC4 | |
| SCHEMBL9402706 | 0.78 | ALDH1A1 (0.44) | KMT2ARAB9ANPC1MAPTMLYCD | |
| SCHEMBL23647979 | 0.78 | OGG1 (0.58) | KMT2ARAB9ANPC1HDAC3HDAC4 | |
| SCHEMBL1897651 | 0.78 | NPC1 (0.62) | KMT2ARAB9ANPC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463989-B1 | N-oxyimidic acid derivatives | SANDOZ LTD (CH) | 1994-12-28 | — | — | EP | disclosed |
| US-5319123-A | Reacting an N-alkoxyamide with an acyl halide in the presence of a hindered base | SANDOZ LTD. (CH) | 1994-06-07 | — | — | US | disclosed |
| EP-0463989-A1 | N-oxyimidic acid derivatives | SANDOZ LTD. (CH) | 1992-01-02 | — | — | EP | disclosed |