Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26766431 | 0.86 | CRHR1 (0.58) | GFERCRHR1HTTSMN1; SMN2GAA | |
| SCHEMBL7684275 | 0.82 | MAPT (0.53) | CRHR1HTTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL7692056 | 0.79 | ALDH1A1 (0.49) | TOP2ATOP2BHTTSMN1; SMN2PDE10A | |
| SCHEMBL7532440 | 0.78 | CYP1A2 (0.56) | HTTSMN1; SMN2GAATSHRKDM4E | |
| SCHEMBL18535287 | 0.78 | KDM4E (0.59) | GFERCRHR1HTTSMN1; SMN2GAA | |
| SCHEMBL7681680 | 0.77 | CRHR1 (0.53) | CRHR1HTTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL1564292 | 0.75 | GAA (0.54) | GFERCRHR1HTTSMN1; SMN2GAA | |
| SCHEMBL437287 | 0.75 | NR4A2 (0.61) | GFERCRHR1HTTSMN1; SMN2GAA | |
| SCHEMBL29393886 | 0.75 | MAPT (0.57) | GFERCRHR1HTTSMN1; SMN2GAA | |
| SCHEMBL316994 | 0.75 | MAPT (0.57) | GFERCRHR1HTTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387821-B1 | 2-Alkyl-4-arylmethylaminoquinolines, their use and medicines containing them | BASF AG (DE) | 1994-08-24 | — | — | EP | disclosed |
| US-5102892-A | Antisecretory agent for gastrointestinal disorders | BASF AKTIENGESELLSCHAFT (DE) | 1992-04-07 | — | — | US | disclosed |
| EP-0387821-A2 | 2-Alkyl-4-arylmethylaminoquinolines, their use and medicines containing them | BASF Aktiengesellschaft (DE) | 1990-09-19 | — | — | EP | disclosed |