Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364207 | 0.84 | RIPK1 (0.39) | HTR7MLYCDALDH1A1SOAT1RIPK1 | |
| SCHEMBL6451749 | 0.84 | CYP3A4 (0.46) | CYP3A4ALDH1A1MEN1KMT2ARIPK1 | |
| SCHEMBL9337221 | 0.82 | RIPK1 (0.46) | ALDH1A1SOAT1RIPK1 | |
| SCHEMBL6453516 | 0.81 | ADORA2A (0.47) | CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL9794550 | 0.79 | SOAT1 (0.45) | ALDH1A1SOAT1RIPK1 | |
| SCHEMBL11427360 | 0.79 | SOAT1 (0.39) | HTR7ALDH1A1SOAT1 | |
| SCHEMBL9794539 | 0.77 | RIPK1 (0.50) | SOAT1RIPK1 | |
| SCHEMBL9340727 | 0.77 | RIPK1 (0.44) | ALDH1A1SOAT1RIPK1 | |
| SCHEMBL4090847 | 0.76 | HTR7 (0.38) | HTR7SOAT1RIPK1 | |
| SCHEMBL6454343 | 0.75 | CYP3A4 (0.42) | CYP3A4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318893-B1 | Titanocenes, their use and N-substituted fluoroanilines | CIBA GEIGY AG (CH) | 1994-01-19 | — | — | EP | disclosed |
| US-5026625-A | Photoinitiators for polymerization of ethylenically unsaturated compounds | CIBA-GEIGY CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0318893-A2 | Titanocenes, their use and N-substituted fluoroanilines | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |