SCHEMBL9364231

SCHEMBL9364231

CCCCn1c(=O)[nH]c(=O)n1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.40
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
PKM P14618 1/20 0.40
PGR P06401 1/20 0.40
RORA P35398 1/20 0.40
RORC P51449 1/20 0.40
RORB Q92753 1/20 0.40
GAA P10253 3/20 0.39
ALDH1A1 P00352 2/20 0.39
ADORA2B P29275 1/20 0.39
GLA P06280 1/20 0.39
ATM Q13315 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29712108 0.94 MEN1 (0.47) MEN1KMT2ANPSR1KDM4EGAA
SCHEMBL8128786 0.76 GSK3A (0.54) SMN1; SMN2NPC1RAB9AMEN1KMT2A
Potassium SCHEMBL11261679 0.74 GSK3A (0.52) SMN1; SMN2NPC1RAB9AMEN1KMT2A
SCHEMBL11271717 0.73 ALDH1A1 (0.46) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL11430292 0.73 NAPRT (0.48) SMN1; SMN2KMT2AKDM4EGAAALDH1A1
SCHEMBL29238914 0.73 NAPRT (0.58) SMN1; SMN2NPC1RAB9AMEN1KMT2A
SCHEMBL11633842 0.72 NTRK1 (0.48) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL11255208 0.72 NAPRT (0.47) SMN1; SMN2KMT2AKDM4EGAAALDH1A1
SCHEMBL23399646 0.71 PTGS2 (0.56) SMN1; SMN2NPC1RAB9AMEN1KMT2A
SCHEMBL23400266 0.71 PTGS2 (0.60) SMN1; SMN2NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0267491-B1 Silver halide light-sensitive photographic material containing a novel yellow coupler KONISHIROKU PHOTO IND (JP) 1994-03-09 EP disclosed
US-4992360-A Silver halide light-sensitive photographic material containing a novel yellow coupler KONICA CORPORATION (JP) 1991-02-12 US disclosed
EP-0267491-A2 Silver halide light-sensitive photographic material containing a novel yellow coupler KONICA CORPORATION (JP) 1988-05-18 EP disclosed