SCHEMBL9360229

SCHEMBL9360229

Oc1cc2ccc(SCc3cnccn3)cc2cc1O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DAO P14920 6/20 0.54
MIF P14174 1/20 0.38
HPGDS O60760 1/20 0.36
IDO1 P14902 1/20 0.33
NOS2 P35228 1/20 0.33
EGFR P00533 2/20 0.33
PDGFRB P09619 2/20 0.33
PDGFRA P16234 2/20 0.33
LMNA P02545 1/20 0.32
STAT3 P40763 1/20 0.32
RAB9A P51151 1/20 0.32
SYK P43405 1/20 0.31
PIEZO1 Q92508 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9360323 0.81 DAO (0.56) DAOLMNARAB9A
SCHEMBL9364471 0.75 KDM4E (0.42) LMNASTAT3RAB9A
SCHEMBL9360303 0.71 IGFBP3 (0.36) DAOMIFLMNASTAT3
SCHEMBL9360309 0.70 DAO (0.35) DAOMIFLMNASTAT3
SCHEMBL6841258 0.70 APEX1 (0.52) DAORAB9A
SCHEMBL14488195 0.70 DAO (1.00) DAO
SCHEMBL9360179 0.68 MAOA (0.51) DAOMIFRAB9A
SCHEMBL9360286 0.68 KMT2A (0.39) LMNASTAT3RAB9A
SCHEMBL19332416 0.68 MAPT (0.50) DAOIDO1RAB9A
SCHEMBL9360293 0.67 KMT2A (0.38) LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0419676-B1 THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME TEIJIN LTD (JP) 1994-12-07 EP disclosed
EP-0419676-A1 THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME TEIJIN LIMITED (JP) 1991-04-03 EP disclosed